Relationship of metabolic markers in Parkinson’s disease
Objective: To investigate the relationship of obesity, Hypertension (HTN), Ischemic heart disease (IHD), Dyslipidemia (DLP), and Diabetes Mellitus (DM) with PD. Background: Parkinson’s disease (PD)…Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells
Objective: The newest candidate growth factor for dopaminergic neurons is Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF). Signaling mechanisms by which MANF protects dopaminergic neurons from ER…Citrus extract A protects dopaminergic neuron by modulating mitochondrial respiration and reactive oxygen species
Objective: This study aims to validate the protective effect of citrus extract A (CEA) against loss of dopamine neurons in PD by dual targeting of…Objective identification of freezing of gait in Parkinson’s disease patients using a triaxial accelerometer
Objective: The aim of this study is to objectively detect and quantify freezing of gait (FOG) in Parkinson’s disease (PD) patients during everyday activities. Background:…Correction of minimal oculomotor disorders improves forward and lateral axial dystonia in Pakinson’s disease
Objective: To evaluate the possible improvement of lateral and forward axial dystonia in PD patients following correction of minimal oculomotor abnormalities including version and saccades…Targeted overexpression of A53T-alpha-synuclein induces progressive neurodegeneration and electrophysiological changes of noradrenergic locus coeruleus neurons – a preclinical model of Parkinson’s disease
Objective: In our present study, we developed a new mouse model to study the time dependent effects of cellular A53T-α-synuclein overexpression in the locus coeruleus,…Relationship between the presence of colonic a-synuclein and MDS research criteria for prodromal PD in patients without manifest motor parkinsonism (PARCAS study)
Objective: The aim of the study was to assess the prevalence of prodromal PD based on the MDS research criteria in a population of patients…Increased bilirubin levels in Parkinson’s disease from southern Spain.
Objective: To evaluate serum bilirubin concentration in Parkinson’s disease (PD) compared to healthy controls (HC) and to investigate its associations with motor and non-motor features…Parkinson’s Disease-Like Pathology in the Rat Brain and Colon Following Methamphetamine Self-Administration
Objective: To determine if Parkinson’s disease (PD)-like pathology occurs in brain and colon following termination of methamphetamine (meth) self-administration. Background: Meth abuse increases the risk…Exploratory Clinical study of role of cerebral dopamine neurotrophic factor (CDNF) mediating endoplasmic reticulum stress (ERS) in Parkinson Disease
Objective: 1: to identify and measure endogenous CDNF levels in peripheral whole blood of healthy control subjects and to examine CNDF expression development profile across the life…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.