CB2R agonist AM1241 reverses the development of MPTP-induced PD and activates the regeneration of DA neurons
Objective: A promising and potential direction to treat PD is to develop new non-dopaminergic drugs without producing dyskinesia, as well as arresting and even reversing…Pairing TMS and physical therapy for treatment of gait and balance disorders in Parkinson’s Disease: a randomized pilot trial
Objective: To explore the feasibility of pairing repetitive transcranial magnetic stimulation (rTMS) back-to-back with standard of care physical therapy (PT) for posture instability and gait…Determinant factors of treatment adherence in Parkinson’s disease
Objective: To determine factors predicting treatment adherence in patients with idiopathic Parkinson’s disease. Background: Parkinson’s disease is the second most common cause of neurodegenerative disease…Closed Loop STN DBS for Tremor in Parkinson’s disease using a Neural or Kinematic Signal
Objective: Compare safety, tolerability, efficiency and efficacy of closed loop DBS (clDBS) of the subthalamic nucleus (STN) for resting tremor in Parkinson’s disease (PD) using…Comparison of neurotoxic potency of a newly produced Botulinum Neurotoxin Type A with onabotulinumtoxinA, incobotulinumtoxinA and BotulinumtoxinA
Objective: This study aims to compare the neurotoxic potency of four different kinds of toxins, accompanied with expression level changes of key factors after BoNT/A…The therapeutic effects of cortical electrical stimulation in an animal model of Parkinson’s disease
Objective: In this study, we first designed the long-term implantable cortical electrical stimulation (CES) module in a rat model of Parkinson's disease (PD). With the…Intrajejunal levodopa infusion (ILI) for Parkinson’s Disease (PD): A Canadian Experience
Objective: To review the benefits and complications of ILI for PD in a tertiary movement disorders center in Canada. Background: ILI has been in use…Protocol for upper-limb kinematic analysis in paediatric movement disorders and relative normality data
Objective: The study proposes a specialised protocol to collect and analyse kinematic data from paediatric patients affected by Movement Disorders (MD). The aim is to…More effective rTMS site for the freezing of gait in Parkinson’s disease
Objective: The aim of study is to find brain stimulation areas showing more effective response. Background: Freezing of gait (FOG) is frustrating problem in Parkinson’s…Design of a randomized, sham-controlled trial of pallidal neurostimulation versus botulinum toxin treatment for cervical dystonia (StimTox-CD)
Objective: In this trial we will assess the efficacy and safety of pallidal deep brain stimulation (DBS) versus botulinum toxin A (BoNT A) therapy in cervical…
