Targeting alpha-Synuclein Aggregation for the Treatment of Parkinson’s Disease
Objective: To develop small molecular weight compounds (SMEs) as disease-modifying agents, which are designed to arrest or even reverse the aggregation process of alpha-synuclein (aSyn)…A qualitative study of the views and experience of people with Parkinson’s disease regarding their footwear
Objective: A qualitative study to determine what people with Parkinson’s disease (PD) wear on their feet at home and outdoors and to increase our understanding…Diphasic Dyskinesias during levodopa-carbidopa intestinal gel (LCIG) infusion: diagnosis and management in clinical practice.
Objective: To describe the occurrence, diagnostic approach, clinical management and outcome of diphasic dyskinesias (Dyskinesias-Improvement-Dyskinesias, DID) in a large group of Parkinson’s Disaese (PD) patients…Barriers to exercise in newly diagnosed Parkinson’s disease
Objective: To evaluate and understand the perceived benefits and barriers towards physical activity in newly-diagnosed people with Parkinson’s disease (PwP). Background: The evidence base to…Combined Motor and Cognitive Training Improves Motor and Cognitive Function in People with Parkinson’s Disease and Freezing of Gait
Objective: Investigate whether combined motor and cognitive training improves motor and cognitive function in people with PD and freezing of gait (FOG). Background: FOG affects…Managing severe dyskinesia in Parkinson’s Disease using 24-hour Levodopa/Carbidopa Intestinal Gel Infusion
Objective: We report the effective treatment of troublesome dyskinesias in Parkinson’s disease (PD), unresponsive to 16-hour daytime infusions, using 24-hour Levodopa/Carbidopa Intestinal Gel (LCIG). Background:…Exercise Trends Reported in Parkinson’s Patients
Objective: To examine trends in type, frequency, and effectiveness of exercise in Parkinson’s patients based on gender, race, and years since diagnosis. Background: Exercise has…Co-speech gestures in Parkinson’s disease (PD)
Objective: We develop an analytical description of co-speech gesture production in PD patients. Background: Communication and expressive behavior problems are frequent in PD patients (Duncan…Interaction of dietary protein with levodopa in Parkinson disease.
Objective: To study the effect of dietary protein on levodopa effectiveness in Parkinson disease (PD) patients. Background: Levodopa transport across the blood brain barrier is…Fibroblasts Implanted in Internal Pallidum of Parkinsonian Macaques Exert L-Dopa-Sparing Activity
Objective: To assess the effects of autologous implantation of fibroblasts in the internal globus pallidus of dyskinetic MPTP-lesioned monkeys upon motor behaviour and L-DOPA response.…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.