Design and discovery of 1,2,4 triazole derivatives as adenosine A2A receptor antagonist against parkinson’s disease
Objective: In the present study, we intended to develop novel 1,2,4 triazole as potent A(2A)AR antagonists against parkinson’s disease. Background: Parkinson’s disease (PD) is a…Alternative Apomorphine Challenge Test
Objective: To propose a new apomorphine challenge test Background: In the standard apomorphine challenge test, the appropriate dose of apomorphine is established by incremental dosing…Neuroprotection and Alleviation of Parkinsonian Phenotypes by Ayurvedic Herbs
Objective: Our laboratory has focused on the herbal treatment of Parkinson’s disease especially by the above two common herbs Withania somnifera (Ws) and Mucuna pruriens…Effects of non-invasive electrical and magnetic stimulation to improve motor and cognitive function in Parkinson’s disease: a meta-analytical review
Objective: This meta-analytical review aims to compare 1) the effects of non-invasive repetitive transcranial magnetic (rTMS) and transcranial electrical stimulation (tES); and 2) identify optimal…Istradefylline improves motor symptoms in Parkinson’s disease: A meta-analysis
Objective: The aim of this meta-analysis was to provide strong evidence for the main and side effects of istradefylline on patients with Parkinson’s disease. Background:…Clinical features and response to botulinum toxin in primary and secondary hemifacial spasm
Objective: To study demographic and clinical features of primary and secondary hemifacial spasm and assess their response to botulinum toxin therapy. Background: Hemifacial spasm (HFS)…Dopamine replacement medication improves acquisition, retention, and transfer of skilled upper extremity movement in people with Parkinson Disease.
Objective: To determine whether i) dopamine replacement medication affects learning of an upper limb (UL) feeding task in people with Parkinson disease (PD), and ii) training…Evaluation of the short-term and long-term effects of an intensive multidisciplinary collective rehabilitation program over 5 weeks in Parkinson’s patients followed in Lyon
Objective: We studied the value of collective (8 patients per group) intensive multidisciplinary collective rehabilitation in the short and long term. Background: Numerous studies have proved…Antisense oligonucleotides containing amido-bridged nucleic acid downregulate SNCA expression and improve motor function in Parkinson’s disease mouse models.
Objective: In this study, we used gapmer-type antisense oligonucleotides (ASOs) containing amido-bridged nucleic acid (AmNA). ASO, short single-stranded stretches of DNA or RNA with complementary…Parkinson’s Disease Medications Availability in Each Philippine Region
Objective: This study aimed to enumerate the different Parkinson’s disease medications in the Philippines and describe the distribution and availability among the 17 regions of…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.