Subthalamic Nucleus Deep Brain Stimulation in Early Stage Parkinson’s Disease Reduces the Risk of Polypharmacy: Five-Year Analysis
Objective: To compare the proportion of subjects on polypharmacy after five years in the deep brain stimulation (DBS) in early stage Parkinson’s disease (PD) pilot…Outcomes of a Prospective, Multicenter International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: To investigate the effectiveness and safety-related real-world outcomes of a multiple-source, constant current Deep Brain Stimulation (DBS) System in the treatment of levodopa-responsive Parkinson’s…Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of DBS for Parkinson’s disease
Objective: To evaluate clinical outcomes in subjects implanted with a Directional Lead for use in the treatment of levodopa-responsive Parkinson’s disease (PD) as part of…INTREPID Trial: A Prospective, Double blinded, Multi-center Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple-Source, Constant-Current Rechargeable System in Parkinson’s Disease
Objective: The objective of the INTREPID clinical trial is to assess the improvement in motor function and quality of life in patients with advanced, levodopa-responsive…Wearing Off Frequency in Different Hoehn-Yahr Stages in Parkinson’s Disease
Objective: To determine wearing off frequency in different stages of Parkinson’s disease (PD). Background: Levodopa is the gold standard in the symptomatic treatment of PD. The…Ambulatory movement measurement in evaluating deep brain stimulation effect in patients with advanced Parkinson’s disease
Objective: To assess the use of the Parkinson's Kinetigraph™ (PKG™) in evaluating the effect of deep brain stimulation (DBS) in patients with advanced Parkinson's disease (PD). Background: Assessment of the effect of DBS on bradykinesia…Preventing Levodopa Induced Dyskinesia with Docosohexanoid Acid in Parkinson Disease
Objective: The purpose of this study was to determine if Docosohexanoic acid (DHA) affects the speed and severity of development of levodopa induced dyskinesia (LID) in subjects starting levodopa (LD).…Long-Term Dopamine Transporter Imaging and Clinical Effects of the Mixed-Lineage Kinase Inhibitor CEP-1347 in the PRECEPT Parkinson Trial
Objective: To assess the imaging and clinical effects of CEP-1347 after treatment discontinuation in the Parkinson Research Examination of CEP-1347 Trial (PRECEPT), a multi-center randomized…Transcranial direct current stimulation enhances consolidation of learning in Parkinson’s disease
Objective: To examine the effects of training combined with transcranial direct current stimulation (tDCS) on writing performance and consolidation of learning in Parkinson’s disease (PD).…Home-based step training using videogame technology in people with Parkinson’s disease: a randomized controlled trial
Objective: To determine the effectiveness of 12 weeks of home-based exergame step training for improving stepping performance, physical and neuropsychological measures associated with falls in…
