MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Post-hoc analyses of the recommended starting dose for Rytary based on “off” time

    N. Modi, S. Khanna, S. Gupta (Hayward, CA, USA)

    Objective: To determine whether correcting for “off” time duration improves the selection of the final LD dose when converting to extended-release carbidopa-levodopa capsules (ER CD-LD,…
  • 2017 International Congress

    Postural Instability is a Predictor for Driving Cessation Among Parkinson’s Disease Drivers: A Study of a Computer-Based 3D Driving Simulator.

    O. Jitkritsadakul, S. Krootjohn, C. Thanawattano, C. Anan, R. Bhidayasiri (Bangkok, Thailand)

    Objective: To develop tests to predict the driving capability of PD patients. Background: Continuing driving competence is a concern for Parkinson’s disease (PD) patients and…
  • 2017 International Congress

    Disease-modifying effect of Zonisamide with the induction of BDNF and TrkB expression

    N. Kanzato (Haebaru-cho, Japan)

    Objective: To evaluate to predictors of the disease-modifying effect of drugs on Parkinson’s disease (DM-PD) according to long-term therapeutic investigation, especially regarding the non-dopaminergic agent…
  • 2017 International Congress

    Tremor’s Glove – An Innovative Electrical Muscle Stimulation Therapy to Treat Intractable Tremor in Parkinson’s Disease Patients: A Randomized Sham-Controlled Trial

    O. Jitkritsadakul, C. Thanawattano, C. Anan, R. Bhidayasiri (Bangkok, Thailand)

    Objective: To investigate the efficacy of a novel EMS device (Tremor’s glove) for reducing intractable resting hand tremor in PD. Background: Intractable resting hand tremor is…
  • 2017 International Congress

    ON-time evolution following one-year open-label opicapone: BIPARK-I study

    J. Ferreira, A. Lees, O. Rascol, W. Poewe, A. Santos, I. Oliveira, B. Hernandez, F. Rocha, P. Soares-da-Silva (Lisbon, Portugal)

    Objective: ON-time evolution following 1-year, open-label (OL), once-daily (QD) opicapone (OPC) treatment in patients with Parkinson’s disease (PD) on levodopa-therapy and with motor fluctuations. Background:…
  • 2017 International Congress

    Results From a Phase 1b Multiple Ascending-Dose Study of PRX002, an Anti–Alpha-Synuclein Monoclonal Antibody, in Patients with Parkinson’s Disease

    J. Jankovic, I. Goodman, B. Safirstein, D. Schenk, G. Kinney, M. Koller, D. Ness, S. Griffith, M. Grundman, J. Soto, S. Ostrowitzki, F. Boess, M. Martin-Facklam, J. Quinn, S. Isaacson, D. Jennings, O. Omidvar, A. Ellenbogen (Houston, TX, USA)

    Objective: To evaluate PRX002 in patients with PD in a double-blind, placebo-controlled, phase 1b multiple ascending-dose study. Background: PRX002 (RG7935) is an investigational monoclonal antibody…
  • 2017 International Congress

    Manual and Verbal guidance during the balance training based in virtual reality is essential for therapeutic results in people with Parkinson’s disease: a randomized clinical trial

    M.E. Pimentel Piemonte, A. Falconi, M. D"Alencar, E. Okamoto (Sao Paulo, Brazil)

    Objective: To compare the effects of balance training in Virtual Reality (VR) supported  by manual and verbal guidance (MVG) versus an identical training in absence…
  • 2017 International Congress

    Randomized Parkinson’s Trial of GDNF Administered via Intermittent Intraputamenal Convection-Enhanced Delivery.

    T.G. Study Group (Bristol, United Kingdom)

    Objective: Assesing the neurorestorative effect of GDNF.  Background: GDNF is a potent neurotrophic factor. A previous placebo-controlled trial, however, at 6 months, failed to demonstrate…
  • 2017 International Congress

    The Importance of Ultrasonographic Evaluation in the Diagnosis of Dysphagia in Parkinson Disease

    E. Umay, E. Ozturk, I. Gundogdu, O. Delibas, B. Gonenli, A. Cakci (Ankara, Turkey)

    Objective: Dysphagia occur frequently in Parkinson’s disease. It include usually some problems to pharyngeal phase.  Background: The aim of this study was to compare the…
  • 2017 International Congress

    A Preliminary Study: Validity and Reliability of Parkinson Fatigue Scale (PFS) in Turkish Patients with Parkinson’s Disease (PD)

    E. Ozturk, E. Ozturk, B. Gonenli Kocer, I. Gundogdu, A. Cakci, E. Umay (Ankara, Turkey)

    Objective: The purpose of this study was to investigate the validity and reliability of the Turkish version of PFS. Background: The PFS is a 16-item…
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