Programming of deep brain stimulators in Parkinson’s disease with early motor complications (EARLYSTIM-study)
Objective: Recently the EARLYSTIM study showed the superior effect of subthalamic stimulation to best medical treatment in Parkinson`s disease with early motor complications. Background: EARLYSTIM…Innovative recruitment strategies accelerate enrollment of genetic mutation carriers in the Parkinson’s Progression Markers Initiative (PPMI)
Objective: Determine feasibility of digital recruitment strategies, centralized screening, and a dedicated referral coordinator to enroll participants with LRRK2 or GBA mutations into PPMI, a…Proprioceptive Focal Stimulation (Equistasi®) may improve gait in severe Parkinson’s disease patients. Gait Analysis double-blind, double-dummy randomized study
Objective: Object of the study was to evaluate the efficacy of Propriocettive Focal Stimulation on Gait in severe Parkinson disease patients by randomized Blind double…Study Design for a Multi-Modal Approach to Understanding Parkinson’s Disease: The Personalized Parkinson Project
Objective: We aim to create a longitudinal dataset of clinical, molecular, imaging, and continuous wearable sensor-based data from a representative Parkinson’s disease (PD) cohort. Data…Improvement in attention/memory domains in advanced Parkinson’s disease patients treated with levodopa-carbidopa intestinal gel is associated with better quality of life
Objective: To evaluate the relationship between non-motor symptom (NMS) severity, quality of life (QoL), and activities of daily living (ADL) in advanced Parkinson’s disease (PD)…Safety of levodopa-carbidopa intestinal gel treatment in advanced Parkinson’s disease patients receiving ≥ 2000 mg daily dose of levodopa
Objective: To examine the safety of levodopa-carbidopa intestinal gel treatment (LCIG, carbidopa-levodopa enteral suspension in the US) in advanced Parkinson’s disease (PD) patients that received…A long-term study on effectiveness of levodopa-carbidopa intestinal gel treatment in advanced Parkinson’s disease patients
Objective: To present the design of and baseline patient characteristics from an ongoing global study assessing the long-term effectiveness of levodopa-carbidopa intestinal gel (LCIG, carbidopa-levodopa…Movement disorder specialists’ determination of eligibility for device aided treatment in advanced Parkinson’s disease: Results from the OBSERVE-PD study
Objective: To characterize the clinical and non-clinical features of ‘advanced’ PD patients considered to be eligible or ineligible for device-aided treatment (DAT) options by movement…Moxibustion for Parkinson’s disease: a systematic review of randomized controlled trials
Objective: This systematic review aimed to evaluate effectiveness and safety of moxibustion therapy for IPD patients. Background: Idiopathic Parkinson’s disease (IPD) is a chronic neurodegenerative…Motor effects and safety of IPX203, an investigational extended-release formulation of carbidopa-levodopa, in advanced Parkinson’s disease: A single-dose study
Objective: Evaluate the efficacy and safety of IPX203 vs. immediate-release (IR) carbidopa-levodopa (CD-LD) and vs. extended-release (ER) CD-LD (IPX066, RYTARY®) in patients with advanced Parkinson’s…
