Associating patient impression of improvement with efficacy endpoints in Parkinson’s disease: A post-hoc analysis of a tozadenant study
Objective: To evaluate whether patient perceived improvement of Parkinson’s disease (PD) symptoms was associated with improvement in efficacy endpoints (mean daily OFF time and ON…A Phase 3 Study of isradipine as a disease modifying agent in patients with early Parkinson’s disease (STEADY-PD III): Baseline characteristics and study update
Objective: To evaluate the efficacy of isradipine 10 mg daily to slow progression of disability in early PD. Background: Isradipine, a dihydropyridine calcium channel antagonist,…The effect of dance and Nordic Walking on balance, gait and motor function in Parkinson’s disease
Objective: To present two rehabilitation programs based on dance and Nordic Walking (NW) for patients with Parkinson’s disease (PD) and their effects. Background: Parkinson’s disease…Feasibility of using a smartphone application for the objective evaluation of Parkinson disease
Objective: To determine the feasibility, reliability, and value of using a smartphone application to longitudinally track motor and non-motor features of Parkinson disease (PD). Further,…Istradefylline and Preladenant as adjuvant therapies for Patients with Parkinson’s disease
Objective: The aim of this meta-analysis is to synthesize evidence about the efficacy of the adenosine receptor antagonists (Istradefylline and Preladenant) for patients with Parkinson’s…DBS Plus: Investigating cell therapy and deep brain stimulation as an approach to alter disease progression and treat motor and non-motor symptoms of Parkinson’s disease
Objective: Investigate safety, feasibility, and potential efficacy of cell therapy combined with DBS to treat and modify symptoms and progression of PD. Background: Our strategy…Efficacy and Safety of Therapeutic Interventions to Treat Motor Symptoms in Late Stage Parkinson’s Disease: A Systematic Review
Objective: Evaluate the efficacy and safety of therapeutic interventions to treat the motor symptoms in late stage PD. Background: PD patients in late stage are…Quantitative demonstration of the efficacy of rotigotine transdermal patch in the treatment of nocturnal hypokinesia: A randomized, placebo-controlled trial using an axial inertial sensor
Objective: To evaluate the efficacy of rotigotine transdermal patch, using a wearable sensor, to treat PD patients with nocturnal immobility. Background: Nocturnal hypokinesia is a…Effect of deep brain stimulation on visuospatial impairment in Parkinson’s disease
Objective: We evaluated postoperative change of visuospatial impairment in the patients with Parkinson’s disease (PD) underwent deep brain stimulation (DBS) to assess the impact of…A novel paradigm of variable frequency deep brain stimulation to improve freezing of gait in Parkinson’s disease
Objective: To determine the effects of a novel deep brain stimulation (DBS) paradigm of combining high and low frequency stimulation in varying patterns (VFS) for…
