Serum levels of polychlorinated biphenyls, CYP2B6 and neurodegenerative disease in the Faroe Islands
Objective: To investigate genetic variability in CYP2B6, PCB levels and Parkinson's disease in the Faroese. Background: Polychlorinated biphenyls (PCBs) are persistent man-made highly toxic pollutants…Epigenome-wide association study of Parkinson’s disease
Objective: To identify gene-specific DNA methylation associated with Parkinson's disease (PD). Background: There is a growing interest in the role of epigenetic DNA methylation (DNAm)…Carrier mediated delivery system bearing dopamine for effective management of parkinsonism
Objective: In the present investigation, amino acid coupled liposome bearing dopamine-HCl were prepared to deliver drug to the brain utilizing receptor-mediated transcytosis for effective management…α-synuclein in peripheral organs decreases in Lewy body disease complicated by Alzheimer’s disease
Objective: To examine whether the degree of α-synuclein (α-Syn) in the peripheral organs of patients with Lewy body disease (LBD: Parkinson's disease, dementia with Lewy…A comprehensive characterisation of the salivary proteome of patients with Parkinson’s disease
Objective: To comprehensively characterise the salivary proteome of patients with Parkinson's disease (PD) and generate potential biomarker candidates for future studies. Background: Saliva may be…Vitamin D in early Parkinson’s disease
Objective: To determine serum 25-hydroxy vitamin D (25OHD) concentration at diagnosis and 18 months in incident Parkinson's disease (PD) compared to controls and to investigate…Microglia P2Y6 receptor is related to Parkinson’s disease and involved in the neuroinflammatory process
Objective: To investigate whether the purinoceptor P2Y6 can be used as a biomarker in the diagnosis and treatment of Parkinson's disease (PD) and the role…Gait initiation in response to emotion-inducing pictures in Parkinson’s disease
Objective: To investigate gait initiation in response to emotion inducing pictures in subjects with Parkinson's disease (PD). Background: Novel pathophysiological models have linked gait disturbances…Monitoring oxidative stress and progression to cell death: From secretome to blood diagnosis
Objective: To achieve a comprehensive method able to distinguish the secretome changes caused by oxidative stress regulation or induction of cell death, and thus be…Faithful SGCE imprinting in iPSC-derived cortical neurons: An endogenous model system of myoclonus-dystonia
Objective: To test the potential of induced pluripotent stem cell (iPSC)-derived cortical neurons from Myoclonus-dystonia (M-D) patients when studying specific epigenetic and brain-specific aspects of…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.