Discrimination of Parkinson’s disease participants from healthy controls using telephone-quality voice recordings
Objective: To test the practicality and efficacy of telephone-quality voice recordings to discriminate Parkinson's disease (PD) participants from healthy controls (HC). Background: Vocal performance degradation…The effect of STN-DBS on movement initiation control is modulated by the noradrenergic system: Evidence of an interaction from a combined pharmacological/DBS/EEG study
Objective: Assessing the role of the noradrenergic system underlying the effect of subthalamic nucleus stimulation (STN-DBS) on akinesia. Background: Slowness in movement initiation, associated with…Gender-age features of autonomic heart rhythm disturbances in Parkinson’s disease patients
Objective: To determine the gender differences and age-dependent features of autonomic heart rhythm disturbances in patients with Parkinson's disease (PD). Background: Autonomic heart rate failures…Brain metabolic profile changes reflect subtle pathological alterations in different murine models of Parkinson’s disease
Objective: Understanding early, and therefore often subtle, disease processes in Parkinson's disease (PD) is essential for the development of disease modifying cures. But in patients,…Apathy phenotype in Parkinson’s disease: Motor and non-motor features
Objective: To evaluate whether apathy is associated with specific motor and non-motor features in patients with Parkinson's disease. Background: In a previous clinical cohort study…Associations between cerebrospinal fluid proteins and cytokines in Parkinson’s disease
Objective: To investigate the relationship between cerebrospinal fluid (CSF) proteins and cytokines, and their correlation with clinical measures in PD. Background: Several studies have investigated…Micro-RNA in cerebrospinal fluid as a biomarker for early diagnosis, differential diagnosis and prognostic marker in Parkinson’s disease
Objective: This study aims to identify specific micro-RNA (miRNA) patterns in cerebrospinal fluid (CSF) of patients with Parkinson's disease (PD) and to compare them with…Protein levels of SV2A and VGLUT1 in brain tissue from patients with Parkinson’s disease, dementia with Lewy bodies and Alzheimer’s disease
Objective: The objective of this study was to investigate whether SV2A and/or VGLUT1 are suitable as markers for synaptic degeneration in neurodegenerative disorders and could…Vagus nerve stimulation as a novel treatment strategy for Parkinson’s disease
Objective: To assess the therapeutic potential of chronic vagus nerve stimulation (VNS) to attenuate the behavioral and neuronal deficits observed in Parkinson's disease (PD) by…Non-motor symptoms profiles in UK white Caucasian and Asian as well as overseas Thai and East Indian patients with Parkinson’s disease
Objective: To compare motor and non-motor symptoms (NMS) in white Caucasian (WC) and Asian patients with Parkinson's disease (PwP) living in the UK as well…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.