Cortical role in the freezing of gait in Parkinson’s disease
Objective: In this study, we aimed to investigate the neural underpinning of freezing of gait (FOG) in Parkinson's disease (PD), especially the role of the…Association of Parkinson’s disease severity and cortical and subcortical cognitive markers
Objective: To assess cortical and subcortical dysfunction in several stages of Parkinson's disease (PD) using the Parkinson's disease-cognitive rating scale (PD-CRS). Background: Cognitive impairment in…Pathophysiological mechanisms of bone mass loss for osteoporosis prevalence in Parkinson’s disease
Objective: Quantify the impact of osteoporosis in Parkinson's disease to know factors that caused bone loss. Background: Parkinson´s disease (PD) and osteoporosis are two conditions…Glutathione status in Parkinson’s disease
Objective: Describe measures of glutathione (GSH) status in a cohort of individuals with Parkinson's disease (PD). Background: It is well established that redox stress contributes…Intrastriatal injection of ionomycin profoundly changes motor response to L-DOPA and its underlying molecular mechanisms
Objective: We investigated whether intrastriatal injection of ionomycin to hemiParkinsonian rats produced changes in L-DOPA responses including LID and analyzed the effects of ionomycin on…Lrrk2 alleles modify host response to microbial infections
Objective: The mechanisms by which allelic changes in LRRK2 modulate the susceptibility to Parkinson's disease, Crohn's disease and leprosy remain unknown. We hypothesized that leucine-rich…Increased cellular co-localization of tau fragment 1-368 and alpha-synuclein in two mouse model of Parkinson’s disease
Objective: To examine the distribution of a novel tau pathology and its interaction with alpha-synuclein in two mouse model of Parkinson's disease (PD). Background: Cleavage…Longitudinal cerebrospinal fluid biomarkers in early Parkinson’s disease and healthy controls
Objective: To analyze changes in levels of four distinct biomarkers in drug-naïve Parkinson's disease (PD) subjects in cerebrospinal fluid (CSF) over 6- and 12 mo…Apocyanin ameliorates post-stroke movement disorder in rats: Possible role of neurochemical and inflammatory alterations
Objective: To study the neuroprotective efficacy of apocynin, a NADPH oxidase inhibitor in 1) alterations of post- stroke motor behaviour, 2) alterations of various neurotransmitter…ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways
Objective: Endosomal sorting required for transport (ESCRT) orchestrates endo-lysosomal soring of ubiquitinated proteins, multivesicular body formation. The aim of this study is to elucidate the…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.