Dietary and Environmental Risk Factors of Parkinson’s Disease: An Integrated Network Pharmacology Approach
Objective: To investigate dietary and environmental determinants of Parkinson’s disease (PD) and related mortality by integrating large-scale clinical phenotyping with network pharmacology and molecular docking…Early Caudate Dopaminergic Loss as an Imaging Biomarker of Cognitive Impairment in Parkinson’s Disease: A Longitudinal Analysis
Objective: The primary objective was to determine whether early pre-synaptic caudate denervation, measured using 123 I ioflupane SPECT quantitative metrics, provides independent and incremental prognostic value…Lipid Alterations in Central Nervous System and Plasma During Early Stages of Parkinson’s Disease
Objective: To identify early lipid alterations in a progressive mouse model of Parkinson’s disease (PD) and to determine whether peripheral lipid signatures reflect lipid changes…One day accelerated 10 Hz rTMS for Focal Hand Dystonia: A Phase II Clinical Trial
Objective: To evaluate the efficacy of four sessions of 10 Hz repetitive transcranial magnetic stimulation delivered in one day (rTMS) to patients with focal hand…Sleep Circadian Rhythms and Brain Disorders: A Large Prospective Cohort and Mendelian randomization Study
Objective: This study aims to investigate the causal relationship between disruptions in sleep circadian rhythms and the risk of seven brain disorders. Background: Disruptions in…Parkinson’s Disease Early Diagnostic and Prognostic Biomarkers Identified by Large-scale Plasma and Cerebrospinal Fluid Proteomic Profiling
Objective: To identify reliable diagnostic and prognostic protein biomarkers for early-stage Parkinson’s disease (PD) using large-scale proteomic profiling of plasma and cerebrospinal fluid (CSF).To identify…Incidence and movement disorders associated with Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in the Princess Maha Chakri Sirindhorn Medical Center (MSMC)
Objective: To identify incidence and clinical features of SREAT patients in MSMC. Background: SREAT patients could present with encephalopathy with various neurological abnormalities, including behavioral…Diagnostic Utility of Routine 1.5T Brainstem Planimetry in Parkinsonism: Evidence from a Vietnamese Cohort
Objective: To compare absolute versus ratio brainstem planimetric measures on routine 1.5T MRI and to identify the best-performing metrics for differentiating PSP and MSA in…Effect of clonazepam on restless legs syndrome in a multiparous pregnant woman
Objective: To report a case of a multiparous pregnant woman with severe restless legs syndrome (RLS) in her seventh pregnancy who was treated with a…Quantitative Assessment of Finger Movement Profile in a Visual-Motor Task Using a Tablet Computer: Application in Multiple System Atrophy
Objective: Building on our prior FMAS validation in Parkinson’s disease (PD), we applied this tablet-based system to quantify finger movement in multiple system atrophy (MSA)…
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