Evaluating Parkinson’s Disease Telehealth in Residential Aged Care
Objective: To evaluate the use, barriers, outcomes, and clinician perspectives of specialist telehealth for Parkinson’s disease (PD) care in residential aged care facilities. Background: Specialist…Treatment-Responsive Holmes Tremor in a Patient with HIV-Associated Hydrocephalus: An Experience from Tertiary Care Hospital
Objective: To report a rare case of Holmes Tremor (HT) secondary to HIV-Associated Hydrocephalus and its successful resolution through a combined surgical and pharmacological approach…The GLP-1 Agonist Paradox in Parkinson’s Disease: A Comparative Analysis of Lixisenatide and Exenatide Phase III Trial Outcomes and Neuroprotective Mechanisms
Objective: To assess the pharmacological and methodological factors underlying the "GLP-1 paradox" by comparing the outcomes of lixisenatide and exenatide, with an emphasis on kinetics,…Unnecessary Ablative Surgery in an Untreated Parkinson’s Disease Patient: Marked Clinical Improvement After Initiation of Dopaminergic Therapy
Objective: To report a case of Parkinson’s disease (PD) in which two ablative procedures were performed without prior dopaminergic therapy, followed by significant clinical improvement…Sleep Circadian Rhythms and Brain Disorders: A Large Prospective Cohort and Mendelian randomization Study
Objective: This study aims to investigate the causal relationship between disruptions in sleep circadian rhythms and the risk of seven brain disorders. Background: Disruptions in…Prediction of Cognitive Decline After STN-DBS in Parkinson’s Disease Using Preoperative Electroencephalography and a Deep Learning Model
Objective: To determine whether preoperative electroencephalography (EEG) combined with deep learning can predict cognitive decline 1 year after subthalamic deep brain stimulation (STN-DBS) in patients…The Impact of Delaying Subcutaneous Device-Aided Therapy for Patients with Advanced Parkinson’s Disease
Objective: This study aims to evaluate the clinical, humanistic, and societal impact of delayed SC therapy in patients with PD. Background: As Parkinson’s disease (PD)…Lipid Alterations in Central Nervous System and Plasma During Early Stages of Parkinson’s Disease
Objective: To identify early lipid alterations in a progressive mouse model of Parkinson’s disease (PD) and to determine whether peripheral lipid signatures reflect lipid changes…Mild Motor Impairments in Rapid Eye Movement Behavior Disorder: Tremor and Bradykinesia
Objective: We investigated patients with RBD to identify mild motor impairments through the objective quantification of sensitive motor control assays. Background: It is established that…Comparative Efficacy of Wrist-Worn Non-Invasive Peripheral Nerve Stimulation for Essential Tremor: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Objective: We aimed to evaluate the efficacy of non-invasive peripheral nerve stimulation (PNS) in reducing clinician-rated tremor severity in essential tremor, assess its effects on…
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