Long-term effects of levodopa/carbidopa intestinal gel infusion in advanced Parkinson’s disease patients: Dutch multicenter retrospective cohort study
Objective: To determine the long-term outcomes of levodopa/carbidopa intestinal gel infusion (LCIG) in advanced Parkinson's disease (PD) patients. Background: LCIG was introduced in the Netherlands…Inhibition of cathepsin D enhances the autophagy lysosome pathway dysfunction and α-synuclein aggregation in experimental parkinsonism
Objective: To explore the mechanism of CTSD inhibition in the dysfunction of autophagy-lysosome pathway and aggregation of α-synuclein in Parkinson's disease. Background: α-synuclein, the main…Rotigotine transdermal patch in Chinese patients with advanced Parkinson’s disease: A randomized, double-blind study
Objective: A multicenter phase III study (SP1037; NCT01646255) to investigate the efficacy and safety of rotigotine in Chinese patients with advanced Parkinson's disease (PD). Background:…Elemental profiles as biomarkers for diagnosis and disease progression of Parkinson’s disease
Objective: This study aims to analyse the elemental profiles in the cerebrospinal fluid (CSF) of patients with idiopathic Parkinson´s disease (PD) and age-matched control patients…The effect of walking speed on postural stability in Parkinson’s disease fallers
Objective: This cross-sectional study aimed to evaluate the effect of imposed faster and slower walking speeds on gait rhythmicity in people with Parkinson's disease (PD)…Effects of videogame step training on gait adaptability in people with Parkinson´s disease – A randomized controlled trial
Objective: To evaluate the effect of home-based interactive videogame step training on gait adaptability performance in people with Parkinson's disease (PD). Background: The ability to…Dopaminergic medication effect on speech in Parkinson’s disease: A kinematic study
Objective: To investigate the effect of levodopa on articulatory movement during Cantonese plosive production in individuals with Parkinson's disease (PD) by comparing kinematic parameters before…A comparison of deep brain stimulation and continuous intrajejunal levodopa infusion in advanced Parkinson’s disease: The INVEST study
Objective: To compare costs and effectiveness of the therapies DBS and CLI in advanced PD. Background: The therapies deep brain stimulation (DBS) and continuous intrajejunale…The correlation between dietary fiber, fluid intake and constipation in patients with Parkinson’s disease
Objective: To clarify the correlation between high dietary fiber, fluid intake and constipation in Parkinson's disease (PD) patients. Background: Constipation is one of the complications…Engrailed enhances dopamine synthesis in healthy dopaminergic neurons
Objective: The aim of the present study was to further elucidate the role of Engrailed in dopamine neurotransmission. Background: Engrailed1 and Engrailed2, collectively Engrailed, are…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.