Adenosine A2A receptor antagonist istradefylline might have efficacy to fatigue and depression in some patients of Parkinson’s disease
Objective: To evaluate the efficacy of istradefylline, a selective adenosine A2A receptor antagonist, for fatigue and depression in Parkinson's disease (PD) patients. Background: Istradefylline is…Voice harmonic amplitude differences before and after LSVT LOUDTM in Parkinson’s disease
Objective: To evaluate voice harmonic amplitudes from acoustic spectra of speech produced by subjects with Parkinson's disease (PD) before and after voice treatment, in order…Diurnal variation of levodopa plasma concentration in patients with Parkinson’s disease
Objective: We analyzed diurnal variation of levodopa plasma concentration in large number of patients with Parkinson's disease (PD) to clarify the pattern of diurnal variation.…Pharmacokinetic profile of ONO-2160/CD (levodopa prodrug/carbidopa) in animal and human
Objective: The objective of this study was to characterize pharmacokinetic profile of levodopa prodrug ONO-2160 in animal and human. Background: Motor complications of Parkinson's disease…Progress in the development of small molecules based on the coumarin core as multifunctional neuroprotective agents
Objective: Taking into account the background of our research group and the knowledge that MAO and ChE activity generates ROS that cause neuronal cell death,…Pisa syndrome in Parkinson’s disease: A mobile orfixed deformity?
Objective: To study of Pisa syndrome in Parkinson's disease. Background: Although Pisa syndrome and scoliosis are sometimes used interchangeably to describe a laterally flexed postural…Suggested criteria for patient selection for therapy with carbidopa/levodopa enteral suspension (CLES)
Objective: To provide suggested guidance on how to select appropriate candidates for therapy with carbidopa/levodopa enteral suspension (CLES) based on published literature. Background: The introduction…New therapeutic algorithm for abnormal posture in Parkinson’s disease and related disorders
Objective: To establish the simple therapeutic algorithm for abnormal posture in Parkinson's disease (PD) or related disorders. Background: Camptocormia or dropped head are sometimes accompanied…Swallowing difficulties in patients with Parkinson’s disease and Parkinsonian syndromes
Objective: To analyze the frequency and severity of swallowing difficulties in patients with Parkinson's disease (PD) and Parkinsonian syndromes. Background: Swallowing difficulties are common in…Predicting medication reduction in Parkinson’s disease patients after deep brain stimulation
Objective: To determine which factors predict medication reduction for Parkinson's disease (PD) patients after deep brain stimulation (DBS) of the bilateral subthalamic nucleus (STN). Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.