Research Information Disclosure In The PPMI Study: Development Of A Disclosure Process
Objective: The Parkinson Progression Markers Initiative (PPMI) is a multinational, longitudinal observational study that collects clinical, imaging, biologic, and genetic data from participants with or…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS). A Phase II clinical trial – ISRCTN99462035.
Objective: The NORAPS Phase II clinical trial seeks to demonstrate safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a…A Phase 2 Randomized Clinical Trial of TAK-071, an Acetylcholine M1 Receptor Positive Allosteric Modulator, in Parkinson Disease with Cognitive Impairment
Objective: To study the safety and efficacy of TAK-071, an M1 positive allosteric modulator, in adults with Parkinson disease (PD) with increased risk for falls…Clinical correlates of apathy in Parkinson´s disease
Objective: To investigate the demographic and clinical correlates of apathy in a group of patients from a Movement Disorders clinic in Latin America. Background: Apathy…Ibudilast, a Phosphodiesterase Inhibitor, Alleviates Huntington’s Disease Pathology through Neuroinflammation Modulation and Signaling Pathway Regulation in a Rat Model
Objective: This research aims to assess whether Ibudilast (IBD), a phosphodiesterase IV (PDE IV) inhibitor, can mitigate the damage induced by 3-nitropropionic acid (3-NP) in…Prodromal RBD and the risk of cognitive impairment in Parkinson’s disease.
Objective: To identify the impact of prodromal RBD in the incidence of cognitive impairment in patients with early PD. Background: The association between sleep disorders…Comparing digital gait and turning measures from a prescribed gait test in the clinic/laboratory versus the same test at home in people with Parkinson’s disease
Objective: We aim to compare the performance of the same prescribed walk test in the laboratory/clinic versus in the home. Background: With the advent of…The Freezing of Gait Change of Direction (FOG-COD) Test: A Novel Measure to Predict Falls
Objective: To examine the relationship between freezing of gait (FOG), falls history, and a novel clinical measure in persons with parkinsonism. Background: Freezing of gait…Possible Sarcopenia and its Association with Physical Activity among Parkinson’s disease Patients
Objective: This study aimed to screen the prevalence of possible sarcopenia and its association with physical activity level in a sample of PD patients. Background:…Response inhibition in patients with Lithium induced Tremor
Objective: In the current study we explored the response inhibition paradigm through Stop Signal Reaction Time (SSRT) task in patients with lithium induced tremor. Background:…
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