A Standardised, Semi-automated Computational Approach to the Analysis of Electrophysiology in Orthostatic Myoclonus
Objective: We sought to develop a standardised, computationally tractable approach to the analysis of electrophysiology in orthostatic myoclonus by developing novel definition criteria for myoclonic…Lived Experiences in early clinical PD: Developing a Framework of a Novel Patient-reported Outcome (PRO) Fit-for-purpose for Disease Modification Therapeutic Trials
Objective: To characterize the lived experience of individuals at a prodromal stage of PD or with a recent clinical diagnosis. Background: There is no validated…GBA Mutations Alter Subthalamic and Nigral Neural Activity in Parkinson’s Disease
Objective: To investigate the neurophysiological basis of Parkinson’s disease (PD) in patients with glucocerebrosidase (GBA) mutations. Background: Alterations in subthalamic neural activity are associated with…Effects of Dynamic Neuro-Cognitive Imagery on FOG in People with Parkinson’s Disease: a Randomized Clinical Trial
Objective: To compare the effects of an experimental intervention (EI) based on DNI with a control intervention (CI) of equal volume and intensity, excluding MP…Random-Order Crossover Trial Assessing the Safety, Feasibility and Exploratory Efficacy of Two Mediterranean-Ketogenic Nutritional Interventions in Parkinson’s Disease
Objective: Assess the feasibility, safety and exploratory efficacy of two Mediterranean-ketogenic dietary interventions in individuals with Parkinson’s disease (PD). Background: Both Mediterranean and ketogenic diets…Two Cases of SCN4A Temperature-Sensitive Sodium Channelopathy: From Dystonia to Myotonia
Objective: To evaluate whether these symptoms, previously categorized as dystonic, might represent manifestations of a temperature-sensitive channelopathy with myotonic features [1]. Background: We report two…Efficacy and Safety of Transcutaneous Auricular Vagal Stimulation on Gait in Patients with Parkinson’s Disease: a Systematic Review
Objective: To perform a systematic review on the efficacy and safety of Transcutaneous auricular vagal stimulation on gait in patients with Parkinson’s disease. Background: PD…Comparative Study of limits of stability Improvements in Young-Onset vs. Late-Onset Parkinson’s Disease Following One-Year Biofeedback Balance Training
Objective: This study aims to assess the impact of balance training and early detection of stability limits in PD on the responsiveness of young and…Addressing Sex and Gender Gaps in Parkinson’s Research: A Multi-Stakeholder Approach
Objective: To describe and address sex and gender gaps in Parkinson’s disease (PD) research through a multidisciplinary, multi-stakeholder approach that includes patient representatives, researchers, clinicians,…The Role of the Immune System in Dystonia: Insights from HLA genotyping
Objective: To characterize the association between Human Leukocyte Antigen (HLA) alleles and dystonia. Background: Dystonia is widely recognized to have great etiologic heterogeneity. A complex…
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