Anti-IgLON5 Encephalitis Presenting as Chronic Progressive Asymmetrical Ataxia and Chorea
Objective: To report a case of gait instability and progressive asymmetrical chorea clinically confirmed as anti-IgLON5 encephalitis. Background: Anti-IgLON5 encephalitis is a rare autoimmune neurological…Accessible Assessment of Ataxia Severity Across Diverse Populations: Integrating Large Datasets, Machine-Learning, and Online Testing
Objective: To explore whether internet-based assessments combined with machine learning approaches can support scalable characterization of ataxia severity. Background: In-person assessments of ataxia severity are…Real-World Outcomes with Directional Deep Brain Stimulation Systems Featuring Multiple Independent Current Control: U.S. Experience
Objective: We report the evaluation of real-world outcomes in patients with Parkinson’s disease (PD) treated with directional deep brain stimulation (DBS) systems incorporating Multiple Independent…Posterior tibial nerve Stimulation in the management of Urinary Disorders in Parkinson’s Disease Experience of the National Hospital Center of Pikine
Objective: Evaluate the efficacy of posterior tibial nerve stimulation in the management of LUTS in patients with PDCompare posterior tibial nerve stimulation to medication Background:…Demystifying the Delivery of Multi-arm Multi-stage Platform Trials for Parkinson’s Disease –Framework and Recommendations from EJS ACT-PD
Objective: To develop a framework of protocol-aligned rater training, educational resources, and inter-site engagement (Stage 1). The secondary aim was to assess the perceived usefulness…Genetic Variation in KCNJ6 Gene Increases Risk of Impulse Disorders in Parkinson’s Disease: A Two-Cohort Study
Objective: To investigate the association between polymorphisms related to reward and punishment processing, and the development of impulse control disorders (ICDs) and compulsive behaviors (CBs)…Beyond Freezing of Gait Episodes in Parkinson’s Disease: Intercritical Kinematic Gait Pattern Matters.
Objective: To search for features discriminating different gait patterns during intercritical FOG-free phases in patients with anamnestic FOG, using spatiotemporal and kinematic variables and machine…Clinical Utility of Neurophysiological Tremor Study Within a Joint Neurology-Neurophysiology Movement Disorders Clinic: One-Year Retrospective Two-Center Study
Objective: To assess concordance between initial clinical diagnosis and neurophysiological tremor study-based diagnosis, combining surface EMG and accelerometry, and to explore the diagnostic utility of…Ante-Mortem Motor Speech Profiles in Postmortem Confirmed Atypical Parkinsonisms
Objective: Differences in motor speech profiles may aid in diagnosis of atypical parkinsonisms. This is a retrospective study that characterizes ante-mortem motor speech profiles in postmortem…Rare Variant Analysis in Parkinson’s Disease Patients Stratified by Polygenic Risk
Objective: To identify rare variants that may contribute to Parkinson’s disease (PD) risk in individuals whose polygenic background does not adequately explain their disease status.…
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