MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Inpatient Multimodal Care Improves Parkinsonian Symptoms Regardless Of Race Or Ethnicity

    N. Elayan, L. Rubin, M. Mccrossin, A. Di Rocco, M. Ghilardi (New York, USA)

    Objective: To verify demographic characteristics of patients with Parkinson’s disease (PD) completing a two-week inpatient multimodal intensive neurorehabilitation and care (iMINC) program and whether iMINC…
  • 2025 International Congress

    Zonisamide for Motor Symptoms and OFF-Time Reduction in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    J. Pitton Rissardo, A. Fornari Caprara (Camden, USA)

    Objective: To evaluate the efficacy and safety of zonisamide as an adjunct therapy for improving motor function and reducing OFF-time in patients with Parkinson’s disease…
  • 2025 International Congress

    Transcutaneous Vagus Nerve Stimulation for Gait and Motor Function in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    J. Pitton Rissardo, A. Fornari Caprara (Camden, USA)

    Objective: To evaluate the effects of transcutaneous vagus nerve stimulation (tVNS) on gait, motor function, and freezing of gait (FOG) in patients with Parkinson’s disease…
  • 2025 International Congress

    Timing And Type Of Adverse Events Following Long-Term Treatment With Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) Infusion – Data From The ELEGANCE Interim Analysis

    N. Smith, B. Amlani (Reading, United Kingdom)

    Objective: To evaluate the type and timing of occurrence of treatment-emergent adverse events (AEs) in people with advanced Parkinson’s disease (PD) following up to one…
  • 2025 International Congress

    COMT-Inhibitors Clinical Experience In Early Motor Fluctuations. Three Months Analysis Of REONPARK Study

    L. López-Manzanares, M. Cerdán Sánchez, T. Delgado Ballestero, B. Solano Vila, J. García-Caldentey, A. Rodríguez-Sanz, H. Brigas, D. Martins, J. Blanco Ameijeiras, M. Rodríguez-de Miguel (Madrid, Spain)

    Objective: The REONPARK study aims to evaluate COMT inhibitors (COMTi) effectiveness and tolerability in alleviating motor complications associated with L-dopa treatment in Parkinson’s disease (PD)…
  • 2025 International Congress

    Adult-onset ataxia with oculomotor apraxia type 4 with severe hypoalbuminemia, generalized edema and obesity

    M. Paucar (Stockholm, Sweden)

    Objective: To report a 45-years-old Swedish man born to non-consanguineous parents affected by an adult-onset syndrome that included insidious pain at onset, hypoalbuminemia, edema, severe…
  • 2025 International Congress

    Clinical Picture of Acute Akinetic Collapse Leading to Multi-Day Immobility in Parkinson’s Disease

    S. Kobayashi, Y. Hagihara, M. Inoue, J. Nakamura, T. Chiba, K. Hokkoku (Tokyo, Japan)

    Objective: To investigate the clinical characteristics of Parkinson's disease (PD) patients who experienced acute akinesia and immobilization requiring emergency medical care. Background: PD patients sometimes…
  • 2025 International Congress

    Positive Relationship Between Improvement in Sleep and Quality of Life During Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion

    R. Hauser, A. Videnovic, P. Odin, K. Chaudhuri, M. Shah, J. Homola, L. Bergmann, R. Gupta, O. Vaou (Tampa, USA)

    Objective: To investigate the relationship between improvements in sleep disturbances and quality of life (QoL) in adults with advanced Parkinson’s disease (aPD) treated with a…
  • 2025 International Congress

    LRRK2 Pathway Inhibition By NEU-411, a Potent, Selective, CNS-Penetrant LRRK2 Inhibitor In Healthy Participants

    C. Wong, S. Dheerendra, T. Dang, F. Nahab, J. Zheng, S. Savage, Z. Pei, C. Wynne, S. Jackson, L. Desnoyers (South San Francisco, USA)

    Objective: The aim of this work was to evaluate LRRK2 pathway modulation by the potent, selective, CNS-penetrant LRRK2 inhibitor NEU-411 in healthy adults and elderly…
  • 2025 International Congress

    Efficacy of ND0612 in Patients at Different Stages of Disease Severity: Subgroup-Analyses From a Randomized, Active-Controlled Study in People With Parkinson’s Disease Experiencing Motor Fluctuations

    H. Sarva, R. Dhall, L. Lopez-Manzanares, J. Kulisevsky, N. Lopes, J. Pereira, S. Isaacson (New York, USA)

    Objective: To evaluate the efficacy of investigational ND0612 in reducing motor fluctuations in patients with Parkinson’s disease (PD) at different stages of disease and/or symptom…
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