What change to expect in duration of benefit per dose when switching from IR CD-LD to IPX203 (ER CD-LD)
Objective: To investigate if duration of benefit (“Good On” time) per dose during immediate-release (IR) carbidopa-levodopa (CD-LD) treatment predicts response to IPX203 conversion. Background: Levodopa’s…Neurofilament light chain in Huntington’s Disease Like 2: a cross-sectional comparison with Huntington’s Disease.
Objective: The objective of this study was to assess the levels of Neurofilament light chain (NfL) in the blood plasma of patients diagnosed with HDL2…Regional Atrophy and Motor Speech in PSP
Objective: This study examined the association of regional atrophy on MRI and motor speech in PSP. Background: Motor speech impairment is common in PSP[1]. Although…The association between perceived walking difficulties and gait speed in people with drug naïve/early PD
Objective: To investigate the association between perceived walking difficulties and gait speed in people with drug naïve or early Parkinson’s disease (PD). Background: Objective aspects…Frequency of Parkinson disease following COVID-19 infection: a two-year retrospective cohort study
Objective: We aimed to utilize a large healthcare research network to determine the risk of developing Parkinson disease following COVID-19 infection compared individuals without COVID-19…Characterization of at-home sleep macrostructure in Parkinson disease using a wearable sleep monitoring device
Objective: Determine the viability of a wearable reduced montage EEG device to record sleep in a population of patients with Parkinson disease (PD). Background: Sleep…Tardive dystonia manifesting in lid-opening apraxia, oromandibular dystonia, and laterocollis after long-term sulpiride use
Objective: We describe a patient who developed tardive dystonia after sulpiride treatment for over two decades. Few cases have been reported[1-3], thus we offer an…Correlation between fatigue, sleep dysfunction and health-related quality of life in Parkinson’s disease patients
Objective: To determine the correlation between fatigue, sleep dysfunction and health-related quality of life in Parkinson’s disease (PD) patients. Background: Fatigue and sleep dysfunction are…miRNAs from blood serum as an early diagnostic biomarker for Parkinson’s disease: A study in an animal model
Objective: This work aims to elucidate miRNA-based biomarkers for the early stages of Parkinson`s Disease diagnosis in a chemically induced PD rat model. Background: The…A 16-week open-label study of the effects of treatment with pimavanserin on activities of daily living in subjects with Parkinson’s disease psychosis (PDP)
Objective: To examine the effects of pimavanserin on activities of daily living during treatment for Parkinson’s Disease psychosis. Background: Accurate assessment of disability associated with…
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