A novel model of care for an integrated movement assessment program (I-MAP) targeted for patients with movement disorders
Objective: To provide an integrated hub where assessment and recommendations on medical, physical, functional, psychosocial needs are made efficiently, and care co-ordination and support services…Bilateral subthalamic nucleus deep brain stimulation in Parkinson’s disease: preoperative predictors of speech worsening
Objective: To find preoperative predictive factors of short-term postoperative speech worsening in a large cohort of consecutive PD patients treated with bilateral STN-DBS. Background: Subthalamic…Deep brain stimulation for the management of movement disorders in Rett syndrome
Objective: We present two patients with Rett syndrome who underwent deep brain stimulation (DBS) for management of action tremor and rigidity. Video segments of the…Predicting clinical response after Gamma Knife thalamotomy in essential tremor
Objective: To determine clinical, surgical and radiological factors associated with tremor reduction after Gamma Knife thalamotomy (GKT) for essential tremor (ET). Background: GKT is a…A single session of aerobic exercise increase EEG gamma band in the motor and sensorimotor areas during usual walking in people with Parkinson’s disease
Objective: We aimed to investigate the effects of a single session of moderate aerobic exercise on electrocortical activity during walking in people with PD. Background:…How do people with Parkinson’s disease experience self-optimization of treatment using digitally supported symptom monitoring?
Objective: The aim of this study was to investigate how people with Parkinson´s disease experience an intervention of optimizing their own medical treatment through digitally…Comparing the outcome under General Anaesthesia (GA) and Monitored Anesthesia Care (MAC) of Subthalamic Nucleus (STN) – Deep Brain Stimulation (DBS) Surgery for Parkinson’s Disease (PD) in Hong Kong – A single center experience
Objective: To evaluate any difference in the clinical outcome under GA and MAC of STN DBS surgery Background: Traditionally, DBS surgery is performed under MAC…The neurological manifestations of PHARC syndrome: a systematic review
Objective: To provide a systematic review of the neurological manifestations of the PHARC syndrome. Background: Polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataracts (PHARC) syndrome…LRRK2 Inhibition by BIIB122/DNL151 Demonstrates Robust Target and Lysosomal Engagement: Pharmacokinetics, Pharmacodynamics and Safety in Phase 1 and Phase 1b Studies in Healthy and Parkinson’s Participants
Objective: To characterize the pharmacokinetics (PK), pharmacodynamics, safety, and exposure-response (E-R) relationships of BIIB122/DNL151 to inform on clinical dose selection. Background: Increased LRRK2 kinase activity…Circadian rhythm and adaptive deep brain stimulation in essential tremor
Objective: We aim to develop a closed-loop adaptive deep brain stimulation (aDBS) system that turns DBS off based on the real-time detection of sleep using…
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