Screening for Genetic Forms in Non-focal Dystonia Patients in Russian Population.
Objective: To assess clinical spectrum of genetic forms of dystonia (GD) in a cohort of Russian patients with non-focal dystonia. Background: Dystonia is the third…Multiplex Proteomic Analysis of Lewy Body Dementia Reveals Cerebrospinal Fluid Biomarkers of Disease Pathophysiology and Progression
Objective: To evaluate the performance of a multiplexed proteomic assay in a large multi-center Lewy Body dementia (LBD) cohort. Background: LBD, which comprises Parkinson’s disease…Plasma proteomic profiles and risk of Parkinson’s disease: a prospective study from UK Biobank
Objective: To identify proteins associated with risk of Parkinson's disease (PD). Background: Alterations in plasma protein levels manifest early in individuals at risk of PD.…Metabolic network signature of quantitative motor effects following deep brain stimulation in Parkinson’s disease
Objective: To integrate [18F]-FDG PET (fPET) and objective motor performance to unravel metabolic networks associated with deep brain stimulation (DBS) outcomes in Parkinson’s disease (PD).…Autoimmune GFAP astrocytopathy as an Etiology of Opsoclonus-Myoclonus-Ataxia Syndrome
Objective: To report a case of opsoclonus-myoclonus-ataxia syndrome (OMAS) due to autoimmune GFAP astrocytopathy. Background: OMAS is associated with brainstem pathology. In adults, common causes…Unraveling the Estrogen-Parkinson’s Disease Link: Methodological Challenges in Meta-Analyzing Reproductive Factors and PD Risk.
Objective: To address key methodological challenges in the methodology of meta-analysis of age at menopause, reproductive lifespan and the risk of Parkinson’s Disease (PD). Background:…Blood levels of Cathepsin B are linked to a reduced risk of Parkinson’s disease
Objective: To assess the causal impact of plasma Cathepsin B (CTSB) levels on Parkinson’s disease (PD) risk. Background: Cathepsin B is a crucial lysosomal cysteine…Associations between Inflammation and Sleep Quality in Parkinson’s Disease: Exploring the Potential Influence of Sex.
Objective: To investigate associations between inflammatory blood markers and sleep quality in Parkinson’s Disease (PD) and explore whether biological sex influences these associations. Background: Inflammation…Neurite Orientation Dispersion and Density Imaging revals reveals white matter microstructural changes in isolated REM sleep behavior disorder
Objective: To characterize white matter microstructural alterations in isolated REM sleep behavior disorder (iRBD) using both conventional diffusion tensor imaging and advanced Neurite Orientation Dispersion…Chronic Exercise and Systemic Inflammation in Parkinson’s Disease: Exploring the Role of Exercise Modality
Objective: To investigate the effects of 12 weeks of cardiovascular, resistance, multimodal training, or a waiting list condition on the concentrations of inflammatory blood markers…
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