Risk factors associated with Parkinson’s disease in the DRC (Case of the Initiative Plus Hospital Center, Kinshasa)
Objective: identify factors that could be associated with Parkinson's disease in Congo Background: In DRCongo, few studies have been published on Parkinson's disease to date.At…Digital Health, Telemedicine, and Artificial Intelligence in Parkinson’s Disease Management During COVID-19: A Narrative Review
Objective: The objective of this narrative review was to evaluate the effectiveness of telemedicine and AI-based technologies used for the remote monitoring and management of…Intestinal Dysbiosis in Parkinson’s Disease: Mechanisms, Clinical Implications, and Therapeutic Perspectives (2015–2025)
Objective: This narrative review aims to consolidate research published from 2015 to 2025 regarding abnormalities in gut microbiota in patients with Parkinson’s disease, emphasizing potential…Juvenile-Onset Parkinsonism With Bilateral Striatal Necrosis Associated With a Pathogenic MT-ND3 Mitochondrial Variant
Objective: To report a case of juvenile-onset parkinsonism associated with bilateral striatal necrosis and a pathogenic MT-ND3 mitochondrial DNA variant, emphasizing an atypical mitochondrial phenotype…Homozygous PRRT2 Frameshift Mutation Presenting with Infantile Onset Seizures and Childhood Episodic Ataxia
Objective: To report a rare presentation of a homozygous PRRT2 frameshift mutation manifesting as infantile-onset seizures followed by childhood episodic gait imbalance. Background: PRRT2 mutations…Rare Variant Analysis in Parkinson’s Disease Patients Stratified by Polygenic Risk
Objective: To identify rare variants that may contribute to Parkinson’s disease (PD) risk in individuals whose polygenic background does not adequately explain their disease status.…VPS13A Disease: 15 Years of Illness Awaiting a Diagnosis
Objective: Objective. Diagnosing a disease with movement disorders is not always easy. It is even more difficult when there is a family history of hereditary…Paroxismal Torticollis Revealing Cervical disc Calcifications in a Child About a Case
Objective: Cervical dystonia in children is rare compared to adults (1), and is often of sequelae or genetic origin (1). The objective of our work…Disabling Holmes Tremor Following Pontine Hemorrhage Accompanied by a Unique Constellation of Movement Disorders
Objective: To report a case of an adult Filipino male who developed delayed complex post-stroke movement disorders following a pontine hemorrhage. Background: Holmes tremor (HT)…Underestimation of Nighttime Sleep Symptoms in Isolated RBD is Associated with Increased Risk of Phenoconversion to Synucleinopathy: A North American Prodromal Synucleinopathy Consortium Study
Objective: To determine whether mismatch between participant (PT) self-perceived and bed partner (BP)–reported sleep symptoms is associated with risk of phenoconversion to synucleinopathy. Background: Patients…
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