Impact of Altered Cerebrovascular Reactivity on Midbrain Degeneration, Perfusion and White Matter
Objective: To evaluate whether altered cerebrovascular reactivity contributes to midbrain degeneration, perfusion abnormalities, or white matter disease in patients with Parkinson’s disease (PD). Background: Cerebrovascular…Automated Imaging Differentiation of Parkinsonism (AIDP): A Prospective 21-site Trial within the Parkinson’s Study Group
Objective: To prospectively test the performance of Automated Imaging Differentiation of Parkinsonism (AIDP), a machine learning based diagnostic biomarker software for Parkinson’s disease (PD), multiple system atrophy Parkinsonian…The Contribution of APOE4 Genotype on Structural MRI in Parkinson’s Disease: A Study from the PPMI Cohort
Objective: To assess the contribution of Apolipoprotein E4 (APOE4) in Parkinson’s Disease (PD)-related cognitive impairment by analyzing its impact on Gray Matter Volume (GMV). Background:…Ultrasonography Markers in Prodromal Parkinson’s Disease
Objective: This study aims to investigate ultrasonography markers as a potential imaging marker in prodromal Parkinson's disease, with the goal of identifying individuals at higher…Dopamine transporter imaging to predict the risk of aspiration in patients with Parkinson’s disease
Objective: To assess the predictive performance of clinical measures, including dopamine transporter (DaT) imaging, for identifying aspiration risk in patients with Parkinson’s disease (PD). Background:…Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD
Objective: To evaluate the associations between striatal and motor asymmetry in Parkinson’s disease with probable RBD compared to without. Background: Parkinson’s disease is typically characterized…Analysis of structural connectivity in relation to change in dopaminergic medication after 6 months of STN-DBS in Parkinson´s disease – a pilot study
Objective: To describe the relationship between structural connectivity and it´s effect on change in levodopa equivalent daily dose (LEDD) in patients 6 months after subthalamic…Cholinergic brain vulnerabilities associate with diabetic comorbidity in Parkinson disease
Objective: We aim to explore differences in brain cholinergic nerve terminal integrity between Parkinson's disease (PD) patients with and without comorbid diabetes, utilizing a highly…Visual Hallucinations and Pareidolias Across the Lewy Body Disease Spectrum
Objective: To systemically evaluate visual hallucinations and illusions in patients across the LBD spectrum and to discover the underlying neural mechanism behind these visual symptoms.…Data-driven image-based subtyping and staging of neurodegeneration in Parkinson’s disease
Objective: We aimed to conduct image-based, data-driven classification of Parkinson’s disease (PD) progression using event-based modeling (EBM) and derive neuropathological insights from the results. Background:…
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