Motion-robust high-resolution imaging of nigrosome-1 in Parkinson’s disease
Objective: To develop a motion-insensitive high-resolution susceptibility weighted imaging (SWI) sequence for evaluating nigrosome-1 in substantia nigra. Background: In Parkinson's disease (PD) increased amounts of…Early GBA-Related Parkinson’s Disease has a Distinct Clinical Phenotype and Cholinergic Innervation
Objective: This study aims to characterize the clinical features and cholinergic innervation of early Parkinson’s disease (PD) patients with GBA mutations (GBA-PD). Background: The GBA-PD…Structural magnetic resonance imaging patterns reflect α-synuclein propagation in a model of Parkinson’s Disease
Objective: To evaluate structural magnetic resonance imaging (MRI) pattern modifications in an α-synuclein model of Parkinson’s disease (PD). Background: As an early driver of α-synucleinopathies’…Clinical and Brain Morphological Characteristics of Early LRRK2-associated Parkinson Disease
Objective: To investigate the impact of LRRK2 mutation in Parkinson disease (PD) and to explore the preclinical markers of LRRK2 mutation carriers who will develop…Microstructural Changes in the Inferior Tuberal Hypothalamus Correlate with Daytime Sleepiness in Lewy Body Disease
Objective: Identify neuroimaging correlates of excessive daytime sleepiness in Lewy body disorders using diffusion MRI. Background: Excessive daytime sleepiness (EDS) is a common and disabling…Whole-brain functional network signature reflecting conversion of isolated REM sleep behavior disorder
Objective: The aim was to investigate the brain functional network alteration /pattern as a measure to identify the conversion from idiopathic rapid eye movement sleep…Connectivity Profile for Increased Apathy Following Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease
Objective: To describe the structural connectivity profile associated with apathy following subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: While STN-DBS…Synaptic Density Loss in Parkinson’s Disease Independent of Age: Preliminary Findings using [18F]SynVesT-1 PET Tracer
Objective: To determine whether synaptic density differs in the brain of people with Parkinson’s disease and healthy controls using the [18F]-SynVesT-1 PET tracer. Background: The…Abnormal basal ganglia-related functional gradient in Parkinson’s disease
Objective: The aim of this research was to investigate the basal ganglia (BG)-related functional gradient alterations and the association between these brain dysfunctions and clinical…Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease
Objective: To investigate the longitudinal relationship between changes in dopamine transporter single-photon emission computed tomography (DaT SPECT) and changes in motor symptom severity in Parkinson’s…
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