Cholinergic deficits in Parkinson Disease
Objective: To determine whether loss of cholinergic projections to cortical and limbic regions contributes to the development of dementia in Parkinson’s disease (PD). Background: PD…Action- and emotion-related language abilities in Slovenian-speaking individuals with Parkinson’s disease – a background normative study
Objective: To prepare action-related (AR) and emotion-related (ER) linguistic stimuli in Slovenian language to test language functions in Parkinson's disease (PD) patients. Background: PD patients…Assessing the optimal pallidal target in deep brain stimulation for Parkinson’s disease: A single-center retrospective review
Objective: To characterize globus pallidus internus (GPi) deep brain stimulation (DBS) active contact location at one-year post-op for Parkinson’s disease (PD) patients at our center.…Serum neurofilament light-chain concentrations in essential tremor: A case-control study
Objective: We sought to investigate the concentrations of serum neurofilament light-chain (NfL) in essential tremor (ET) patients and healthy controls. Background: Essential tremor is a…A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson’s Disease (PADOVA): Rationale, Design, and Baseline Data
Objective: The study will evaluate the efficacy and safety of prasinezumab in individuals with early-stage Parkinson's disease (PD) on stable symptomatic therapy. Background: Available treatments…Impaired structural connectivity in Parkinson’s disease with probable RBD
Objective: To characterize structural connectivity through whole-brain network-based statistics and graph theory implementation in treated Parkinson’s disease (PD) patients with probable REM sleep behavior disorder…Development of an Item Bank for Assessing Psychosis in Parkinson’s Disease: A Systematic Review
Objective: This study aimed to develop an item bank for assessing psychosis in Parkinson's disease (PD). Background: Psychosis is a common and debilitating symptom in…Co-designing Digital Technologies to improve Clinical Care in People with Parkinson’s Disease
Objective: To develop a co-design methodology and test the usability and acceptability of three digital health technologies for people with Parkinson’s Disease (PwP) Background: The…Exploring brain mechanisms of identity attribution in presence hallucinations of Parkinsonian origin
Objective: Study cognitive, behavioral correlates of identity of presence hallucinations in Parkinson’s disease. Background: Presence hallucination (PH), the sensation that someone is nearby when no…A human tissue engineered nigrostriatal system as a testbed for understanding PD pathophysiology and therapeutic development
Objective: The objective of these studies is to develop a tissue engineered nigrostriatal system involving human dopaminergic and striatal cells to recapitulate many of the…
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