Temporal dynamics and longitudinal predictors of apathy in Parkinson’s disease
Objective: To determine how apathy varies across different disease stages of Parkinson’s disease (PD) and the longitudinal predictors of its development, using a large PD…Goals for Improvement in Essential Tremor Patients Following Focused Ultrasound VIM Thalamotomy
Objective: To report the most common expectations prior to focused ultrasound (FUS) treatment in essential tremor (ET) patients using the Goal Attainment Scaling method (GAS).…Safety and Tolerability of Apomorphine Sublingual Film and Subcutaneous Apomorphine for the Treatment of OFF Episodes in Parkinson’s Disease
Objective: Evaluate safety and tolerability of apomorphine sublingual film (SL-APO) vs subcutaneous apomorphine (SC-APO) for the treatment of OFF episodes in patients with Parkinson’s disease…Estimating the Meaningful Within-Patient Change Threshold for the MDS-UPDRS Part III
Objective: To estimate the meaningful within-patient worsening threshold (MWPWT) of the Movement Disorders Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS Part III in early-stage Parkinson's disease…Illusion of semi-inverted posture during High Frequency Ultrasound Stimulation thalamotomy for tremor
Objective: In this study, we focused on the transient sensation of being tilted along the vertical axis during MRI-guided focused ultrasound (MRgFUS) for tremor. We…Gene Expression Quantification to Assess Frataxin Replacement Therapies in Friedreich’s Ataxia
Objective: To identify genetic disease and efficacy markers for Friedreich’s ataxia (FRDA) Background: FRDA is a genetic disease caused by decreased expression of the mitochondrial…Atypical parkinsonism related to a rare variant in the PLA2G6 gene
Objective: To describe a patient with atypical parkinsonism, carrier of a rare PLA2G6 gene variant. Background: PLA2G6-associated neurodegeneration (PLAN) results from mutations in PLA2G6 gene…“Mirror” jaw movements in parkinsonian patients
Objective: To describe synchronous involuntary rhythmic jaw movements during voluntary hand movements in parkinsonian patients. We called them "mirror" jaw movements. Background: Mirror movements (MM)…Measuring functional cognition with the Short Weekly Calendar Planning Activity in patients with Parkinson’s disease and non-manifesting LRRK2 and GBA carriers
Objective: The aims of this study were to explore the feasibility of the short Weekly Calendar Planning Activity (WCPA-10) to investigate functional cognition in patients…Impact of two different rechargeable pulse generators on parkinsonian patients with deep brain stimulation
Objective: This study compared the recharging frequency and duration, perceived impact and self-management of recharging, and motor symptom suppression in fifteen PD patients who underwent…
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