Elucidating multimodal endophenotypes of APOE-ε4 in α-synucleinopathies
Objective: To systematically identify phenotypes that consistently associate with the ε4-allele of apolipoprotein E (APOE-ε4) in α-synucleinopathies. Background: The APOE-ε4 presents an elevated risk not…Perampanel inhibits α-synuclein transmission in Parkinson’s disease models
Objective: To examine the effect of perampanel, an antiepileptic drug, on α-synuclein transmission in cultured cells and mouse models of Parkinson’s disease. Background: The intercellular transmission of pathogenic proteins…Central and Peripheral neurological manifestations of COVID-19 in a cohort of patients with Parkinson’s disease.
Objective: To describe central and peripheral neurological manifestations in patients with COVID-19 and Parkinson’s disease. Background: COVID-19 is associated with central and peripheral neurological manifestations.…Arm swing instructions alter interlimb coordination but not prefrontal cortex activity of Parkinson’s disease persons.
Objective: This study compared the prefrontal cortex activity and interlimb coordination between PD persons and neurotypical individuals after receiving instructions to increase arm swing amplitude…Sleep disorders and future diagnosis of parkinsonism: a prospective study using the Canadian Longitudinal Study on Aging
Objective: To determine whether symptoms of insomnia, somnolence, apnea, and restless legs syndrome predict the diagnosis of parkinsonism after three years of follow-up. Background: Earlier…Cognitive assessment of Parkinson’s Disease patients in a Northeast Brazilian population: Current Challenges
Objective: To evaluate the influence of education level in the Mini-Mental Status Examination (MMSE) score in Parkinson’s Disease (PD) patients in a northeast Brazilian sample.…ASSOCIATION BETWEEN INSULIN RESISTANCE AND DEVELOPMENT OF DEMENTIA IN PATIENTS WITH PARKINSON´S DISEASE
Objective: The main objective of the study was to analyze the association between insulin resistance (IR ) at diagnosis and the development of dementia in…Shannon entropy: a novel tool for assessing pentagon drawing in Parkinson’s disease
Objective: We used a digitizing tablet during PCT as a potential tool for assessing early cognitive deficits in PD yet without major cognitive impairment. We…Plasma phosphorylated α-synuclein relates to cognitive impairment in patients with Parkinson’s disease
Objective: To investigate whether plasma phosphorylated α-synuclein (p-syn) were associated with cognitive function in Parkinson’s disease (PD). Background: Parkinson’s disease (PD) is the second most…Motor skills of walking in Parkinson’s disease: towards a better understanding of the cognitive abilities implicated in F8WT.
Objective: to evaluate disease related and cognitive features involved in motor skills of walking in people with Parkinson’s disease (PWP). Background: curved path walking and…
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