The Role Imposed by The High-Mobility Group Box 1 (HMGB1) Protein in MPTP-Induced Zebrafish Model of Parkinson’s Disease
Objective: This study aims to investigate the role of HMGB1 protein in mediating neuroinflammatory-induced parkinsonian movement disorder of the MPTP-induced zebrafish model of Parkinson's disease…Biomarker candidates – Peptides identified to be differentially abundant in cerebrospinal fluid of patients with Parkinson´s disease
Objective: The aim of this study was to identify cerebrospinal fluid peptides that are differential in the cerebrospinal fluid of patients with Parkinson´s disease. Those…Metabolic alterations in a Drosophila model of Parkinson’s disease
Objective: Identification of metabolic alterations that could be contributing to Parkinson’s disease (PD) physiopathology and become new biomarkers or therapeutic targets for the disease. Background:…Whole-transcriptome analysis of monocyte-derived macrophages from patients with Parkinson’s disease associated with mutations in the GBA gene
Objective: To understand specific molecular features of Parkinson’s disease associated with mutations in the GBA gene (GBA-PD), we analyzed the gene expression profile of peripheral-blood…Functional connectivity as an early marker of indication for deep brain stimulation treatment in Parkinson’s disease (PD)
Objective: To identify functional neuroimaging patterns anticipating the clinical indication for deep brain stimulation (DBS) in patients with PD. Background: DBS has become a well-established…Motor cerebro-cerebellar networks breakdown among different subtypes of Parkinson’s disease
Objective: The aim of this study was to investigate functional alterations within motor circuits of the cerebro-cerebellar system in tremor-dominant (TD) and postural instability and…Association between Hippocampal Subfields, CSF Biomarkers, and Cognition in non-demented Parkinson’s patients
Objective: To determine whether hippocampal subfield volumes in non-demented Parkinson’s Disease (PD) are primarily predicted by cognition or CSF β-amyloid 1–42 (Aβ42) levels. Background: The…Longitudinal change in thalamic white matter macrostructure and volume in Parkinson’s disease depression
Objective: To investigate thalamic subnuclei volume and macrostructural white matter changes in Parkinson’s disease (PD) depression. Background: Depression is the most common neuropsychiatric feature of…Interest of optical coherence tomography in Parkinson’s disease
Objective: To compare optical coherence tomography (OCT) results of retinal thickness (RT) and retinal nerve fiber layer (RNFLT) thickness of patients with idiopathic Parkinson's disease…Perivascular spaces in the basal ganglia and long-term motor prognosis in newly diagnosed Parkinson’s disease
Objective: To investigate the association between enlarged perivascular spaces (PVSs) in the basal ganglia (BG-PVSs) and long-term motor outcomes in Parkinson’s disease (PD). Background: PVSs…
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