Case report: Parkinsonim with dyskinesia secondary to amyloid angiopathy
Objective: To report a case of parkinsonism secondary to amyloid angiopathy and discuss the pathophysiology and treatment of this entity. Background: Cerebral amyloid angiopathy is…Levodopa Carbidopa Intestinal Gel in Patients with Deep Brain Stimulation in Parkinson’s disease- First case series from Middle-East Region
Objective: The objective is to report unique and challenging cases, who had successful control of Parkinson’s disease (PD) symptoms with combination therapy of Deep Brain…NPC1 is not a PD risk factor gene
Objective: To test the hypothesis of NPC1 to be a PD risk factor gene. Background: The many etiologies of PD include genetic risk factors. The…A Case of Neurodegeneration with Brain Iron Accumulation with novel Adaptor Protein-4 M1 subunit mutation
Objective: To present a patient with clinical and radiological features of neurodegeneration with brain iron accumulation (NBIA) due to a novel variant mutation in adaptor…Fragile X Associated Tremor and Ataxia Syndrome (FXTAS) presents with widespread reactive gliosis and white-matter specific astrocyte degeneration
Objective: We will characterize neuropathological alterations of astrocytes in different regions of the FXTAS brain. Background: FXTAS is a progressive neurodegenerative disorder that occurs in…Phase 2 study evaluating safety, PK/PD, biomarkers, and efficacy of ANX005 in patients with Huntington’s disease (HD)
Objective: To assess the safety, PK/PD, exploratory biomarkers, and efficacy of ANX005 in patients with, or at risk for, manifest HD. Background: Increased complement activation…“Belly Dance Tremor” – Hip and Truncal tremor in Parkinson’s disease
Objective: To report unusual presentation of Young-Onset Parkinson’s disease with disabling hip and trunk rest tremor resembling “belly dance”. Background: Proximal tremor is not commonly…Reconfiguration of Functional Motor Connectome after MRgFUS Vim Thalamotomy in Essential Tremors
Objective: Our primary endpoint was to verify whether rs-FC between tremor-related areas was effectively modulated by MRgFUS at 1 and 3 months post-operatively. Alongside, we…Evaluation of ocular perfusion in Parkinson’s disease and association with clinical manifestations.
Objective: To evaluate optic nerve head and macular perfusion in subjects with Parkinson's disease (PD) and its association with clinical manifestations. Background: PD is associated…COMT polymorphism as a genetic factor in levodopa-induced dyskinesia development in Russian patients with Parkinson’s disease
Objective: We examined the influence of single nucleotide polymorphisms (SNPs) in specific genes on levodopa-induced dyskinesia development in Parkinson’s disease patients Background: Levodopa-induced dyskinesia (LID)…
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