SETTING UP A PEDIATRIC DEEP BRAIN STIMULATION UNIT
Objective: Describe our 2-year experience establishing a pediatric deep brain stimulation (pDBS) service in a tertiary hospital and report our outcomes. Background: DBS is a…PD GENEration Clinical Phase: Genetic Diagnostic Yield and Clinical Characteristics
Objective: To assess the frequency of reportable variants in major genes associated with Parkinson’s disease (PD) and identify clinical predictors of positive genetic test results.…AN ATYPICAL ONSET OF PRIMARY FAMILIAL BRAIN CALCIFICATION: A CASE REPORT.
Objective: To describe a case of PFBC with atypical clinical onset. Background: Primary Familial Brain Calcification (PFBC), also known as Fahr's Disease, is a rare…Chewing camel in stump
Objective: We report an interesting case of jumpy stump, where the stump movements are different from those previously reported as myoclonic or choreic movements. Background:…Five for the price of one- A multidirectional micro-electrode recordings for DBS Surgery
Objective: To examine the use of a multidirectional micro electrode during Deep Brain Stimulation (DBS) surgery for Parkinson's Disease (PD) in 9 patients. Background: Micro-Electrode…Efficacy of Magnetic resonance-guided focused ultrasound thalamotomy (MRgFUS thalamotomy) for refractory essential tremor (ET)-single center experience.
Objective: To assess the efficacy of MRgFUS thalamotomy in patients with ET. Background: MRgFUS thalamotomy can improve tremor in patients with refractory ET[1]. Method: Data…Perceive: A data extraction and analysis toolbox for brain signals from sensing enabled deep brain stimulators
Objective: Develop an open source toolbox that facilitates data extraction, analysis, artifact correction and standardization for the DBS research community. Background: Novel sensing enabled implantable…Pallidal beta activity correlates with stimulation-induced bradykinesia in dystonia patients
Objective: Identify a neurophysiological correlate of stimulation-induced bradykinesia in dystonia Background: Bradykinesia is a known side-effect of pallidal deep brain stimulation (DBS) in dystonia patients…A Phase 2 Randomized, Double-blind, Placebo-controlled Trial of PRAX-944 for the Treatment of Essential Tremor
Objective: Evaluate the tolerability, safety and efficacy of PRAX-944, a selective small molecule T-type calcium channel blocker, for treatment of essential tremor (ET). Background: Essential…The profile of dysautonomia in the early stages of Parkinson’s disease and multiple system atrophy: the importance of using the SCOPA-AUT scale
Objective: To examine the profile of autonomic dysfunction and the utility of the SCOPA-AUT scale in distinguishing patients with early Parkinson's disease (PD) and MSA-parkinsonism (MSA-P)…
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