Exploring the Causal Role of Mitochondria-related Genes in Parkinson’s Disease through Multi-Omics Mendelian Randomization
Objective: To investigate the causal roles of mitochondria-related gene expression in the pathogenesis of Parkinson's Disease (PD). Background: Mitochondria-related gene expression has been implicated in…Single centre experience with subcutaneous foslevodopa/foscarbidopa for GBA Parkinson’s disease
Objective: To describe the clinical outcomes of two patients with GBA Parkinson’s disease (GBA-PD) and severe motor fluctuations treated with subcutaneous foslevodopa/foscarbidopa (fld/fcd) infusion. Background:…Cerebellar Network Compensation in Parkinson’s Disease: Functional Connectivity Across Motor and Cognitive Circuits
Objective: To investigate whether alterations in cerebellar connectivity with cortical and basal ganglia networks in Parkinson’s disease (PD) represent compensatory network adaptations related to dopaminergic…Kinetic–rest tremor polarity for differentiating dystonic tremor and Parkinson’s disease
Objective: To characterize ordinal patterns of tremor amplitude across rest, postural, and kinetic conditions in dystonic tremor (DT) and Parkinson's disease (PD) using accelerometry, and…Beyond Freezing of Gait Episodes in Parkinson’s Disease: Intercritical Kinematic Gait Pattern Matters.
Objective: To search for features discriminating different gait patterns during intercritical FOG-free phases in patients with anamnestic FOG, using spatiotemporal and kinematic variables and machine…Efficacy and Safety of Mesdopetam (IRL790) for Levodopa Induced Dyskinesia in Parkinson’s Disease: A Meta analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy and safety of mesdopetam compared with placebo for levodopa‑induced dyskinesia (LID) in Parkinson’s disease (PD). Background: Mesdopetam (IRL790) is a…Intestinal Dysbiosis in Parkinson’s Disease: Mechanisms, Clinical Implications, and Therapeutic Perspectives (2015–2025)
Objective: This narrative review aims to consolidate research published from 2015 to 2025 regarding abnormalities in gut microbiota in patients with Parkinson’s disease, emphasizing potential…Risk of Deep Venous Thrombosis in Patients With Parkinson’s Disease: A Meta‑Analysis of Observational Studies
Objective: To compare the risk of deep venous thrombosis (DVT) in patients with Parkinson’s disease (PD) versus non‑PD. Background: Patients with PD may have an…Tongue Fasciculations in Amyotrophic Lateral Sclerosis Compared Between Electromyography and Transoral Ultrasonography
Objective: To compare the detection of tongue fasciculations between electromyography (EMG) and transoral motion-mode ultrasonography (TOMU) in patients with amyotrophic lateral sclerosis (ALS), and to…Accessible Assessment of Ataxia Severity Across Diverse Populations: Integrating Large Datasets, Machine-Learning, and Online Testing
Objective: To explore whether internet-based assessments combined with machine learning approaches can support scalable characterization of ataxia severity. Background: In-person assessments of ataxia severity are…
- « Previous Page
- 1
- …
- 86
- 87
- 88
- 89
- 90
- …
- 1942
- Next Page »