Dysfunctional resting connectivity in early stage of Parkinson’s disease is indistinguishable from connectivity in REM sleep behaviour disorder
Objective: To investigate the differences in functional connectivity among healthy subjects (HC), patients with REM sleep behaviour disorder (RBD) and levodopa-naïve patients in early stage…Altered Resting-state Neural Activity in Parkinson’s Disease with Depression: a controlled study based on original meta-analysis results
Objective: Depression is a common non-motor symptom in Parkinson’s disease (PD), while its underlying pathophysiology remains unclear. Previous functional magnetic resonance imaging (fMRI) studies reported…Motor symptom lateralization influences cortico-striatal functional connectivity in Parkinson’s disease
Objective: To evaluate the effect of lateralization on various cortico-striatal circuits through resting state functional MRI. Background: Striatum is unevenly impaired bilaterally in Parkinson’s disease.…Regional brain iron and gene expression variation in Parkinson’s disease
Objective: To shed light on the genes underlying increased cortical iron deposition in Parkinson’s disease (PD). Background: Oxidative stress secondary to brain iron accumulation is…Progression of brain atrophy in Parkinson’s disease is shaped by connectome and local vulnerability
Objective: Using MRI data, the aim of this longitudinal study was to map the progression of brain atrophy over four years and relate it to…Brainstem planimetry in Parkinson’s disease with REM behaviour disorder.
Objective: To investigate the association between brainstem planimetry and REM behaviour disorder (RBD) in de novo Parkinson’s disease (PD). Background: RBD is associated with a…VMAT2 availability in Parkinson’s Disease with Rapid Eye Movement Sleep Behaviour Disorder
Objective: To use [11C]DTBZ PET imaging to explore vesicular monoamine transporter 2 (VMAT2) availability in Parkinson’s disease (PD) with and without rapid eye movement sleep…Factors contributing to prefrontal cortical activity during walking and its response to dual-tasking in Parkinson’s disease
Objective: We examined the contribution of clinical, cognitive, and gait characteristics to prefrontal cortex (PFC) activity during walking and its response to dual-task in people…Resting state functional MRI network assortativity is increased in Parkinson’s disease
Objective: In previous imaging studies, we have that patients with Parkinson’s disease (PD) express a distinct brain network known as the Parkinson’s disease-related pattern (PDRP).…The role of network connectivity in shaping the progression of cortical atrophy in Parkinson’s disease
Objective: We aimed to map the progression of cortical thinning and to test whether this pattern is constrained by network connectivity in the brain. Background:…
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