Session Information
Date: Thursday, June 8, 2017
Session Title: Dystonia
Session Time: 1:15pm-2:45pm
Location: Exhibit Hall C
Objective: To assess the frequency, location and predictors of tremor in Indian patients with primary dystonia.
Background: Tremor is now recognized to be a frequent accompaniment of dystonia. The pattern, location and predictors of tremor in Indian patients with primary dystonia are not well characterized.
Methods: We conducted a prospective-observational study including consecutive patients with primary dystonia. Subjects underwent a structured neurological examination to document the presence, distribution and clinical features of tremor and dystonia.
Results: 143 subjects with primary dystonia were recruited including 24.5% with early onset dystonia. Tremor in at least one site was noted in 53.8%. Upper limb tremor was most common (42.7%) followed by head (26.6%), voice (6.3%), jaw (2.8%), lower limb (2.8%) and facial (0.7%) tremor. Tremor and dystonia were in the same body part (dystonic tremor) in 77.9% and in separate regions (tremor associated with dystonia) in 3.9%. Upper limb tremor was postural in 98.7%, at rest in 41.6%. Null point was present in 41.6%. On multivariate analysis (binary logistic regression) current age (for 10-year increment in age OR=1.66 [95%CI 1.23-2.23], p=0.001) and onset at a non-cranial site (OR=6.86 [95%CI 1.06-44.64], p=0.044) were independent predictors of tremor.
Conclusions: In this clinic based study, tremor was seen in up to one half of patients with primary dystonia. Advancing age and onset of dystonia at a non-cranial site were associated with tremor in this group of patients.
*This work was supported by and done wholly at the Sree Chitra Tirunal Institute for Medical Sciences, Trivandrum. The presenting author is currently Assistant Professor, Department of Neurology, All India Institute of Medical Sciences, New Delhi.
References: This work was wholly done at and supported by the Sree Chitra Tirunal Institute for Medical Sciences, Trivandrum, India. The first author is presently Assistant Professor (Neurology) at the All India Institute of Medical Sciences, New Delhi, India.
To cite this abstract in AMA style:
R. Rajan, S. Zafer, S. Krishnan, A. Kishore. Pattern and Predictors Of Tremor In Patients With Primary Dystonia [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/pattern-and-predictors-of-tremor-in-patients-with-primary-dystonia/. Accessed June 14, 2025.« Back to 2017 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/pattern-and-predictors-of-tremor-in-patients-with-primary-dystonia/