Objective: The aim of the present study was to analyze the change in burden and strain after a 2-year follow-up in a cohort of caregivers of patients with Parkinson´s disease (PD)and also to identify predictors of these changes.
Background: Caregiver burden in PD has been studied in many cross-sectional studies but poorly in longitudinal ones.
Method: PD patients and their caregivers who were recruited from January/2016 to November/2017 from 35 centers of Spain from the COPPADIS cohort were included in the study. They were evaluatedagain at 2-year follow-up. Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI) and Caregiver Strain Index (CSI) at
baseline (V0) and at 2-year follow-up (V2). General linear model repeated measure and lineal regression models were applied.
Results: One hundred and ninety-two PD patients (63.96 ± 8.74 years old; 63% males) and their principal caregiver were included. Mean age of the caregiver was 58.82 ± 11.71 years old and 69.3% of them were females.After the 2-year follow-up, the mean ZCBI score significantly increased by 31.4% (from 13.2 ± 11.31 to 17.35 ± 13.44; <0.0001; Cohen´s effect size = 0.51) whereas the mean CSI score by 26.5% (from 1.89 ± 2.17 to 2.39 ± 2.05; p<0.0001; Cohen´s effect size = 0.34). The percentage of caregivers with little or no burden (ZCBI 0-20) decreased from 77.1% at V0 to 67.7% at V2 (p<0.0001). At V2, 8.3% of caregivers had high level of stress (CSI 7-13)compared to 4.7% at V0 (p=0.090). Caregiver´s mood impairment from V0 to V2 was the strongest factor associated with an increase from V0 to V2 on the total score of the ZCBI (β=0.416; p<0.0001) (Table 1) and CSI (β=0.277; p=0.001) (Table 2).
Conclusion: Burden and strain were impaired in caregivers of PD patients after a 2-year follow-up. Mood changes in the caregiver is a key aspectrelated to caregiver burden increase.
To cite this abstract in AMA style:
C. Cores Bartolomé, D. Santos García, T. Fonticoba, M. Feal Painceiras, E. Suarez Castro, C. Martinez Miro, S. Jesus Maestre, M. Aguilar, P. Pastor, L. Planellas, M. Cosgaya, J. Garcia Caldentey, N. Caballol, I. Legarda, J. Hernandez Vara, I. Cabo, L. Lopez Manzanares, I. Gonzalez Aramburu, MA. Avila Rivera, V. Gomez Mayordomo, V. Nogueira, V. Puente, J. Garcia-Soto, C. Borrue, B. Solano Vila, M. Alvarez Sauco, L. Vela, S. Escalante, E. Cubo, F. Carrillo Padilla, JC. Martinez Castrillo, P. Sanchez Alonso, MG. Alonso Losada, MI. Morales Casado, I. Gaston, J. Kulisevsky, M. Blazquez Estrada, M. Seijo, J. Ruiz Martinez, C. Valero, M. Kurtis, O. de Fabregues, J. Gonzalez Ardura, R. Alonso Redondo, C. Ordas, LM. Lopez Diaz, D. Mcafee, P. Martinez Martin, P. Mir. Predictors of the change in burden and strain among caregivers of Parkinson’s disease patients [abstract]. Mov Disord. 2022; 37 (suppl 2). https://www.mdsabstracts.org/abstract/predictors-of-the-change-in-burden-and-strain-among-caregivers-of-parkinsons-disease-patients/. Accessed May 13, 2025.« Back to 2022 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/predictors-of-the-change-in-burden-and-strain-among-caregivers-of-parkinsons-disease-patients/