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Restless leg syndrome in Neuro-Behcet’s and Behcet’s disease

M. Kuzu Kumcu, S. Erdoğan, M. Sorgun, C. Yücesan (Ankara, Turkey)

Meeting: 2019 International Congress

Abstract Number: 585

Keywords: Anxiety, Depression, Restless legs syndrome(RLS): Etiology and Pathogenesis

Session Information

Date: Monday, September 23, 2019

Session Title: Restless Leg Syndrome, RBD and Other Sleep Disorders

Session Time: 1:45pm-3:15pm

Location: Les Muses Terrace, Level 3

Objective: The goal of this study is the comparison of the restless leg syndrome frequency in the BD and NBD patients and also to investigate whether depression and anxiety have any effect on the presence of RLS in both groups.

Background: A bunch of studies showed that restless leg syndrome (RLS) may be more frequent in the neuro-Behçet’s disease (NBD).

Method: Patients who were diagnosed with BD and NBD at Ankara University İbni-Sina Hospital multidisciplinary outpatient Behçet’s disease clinic and outpatient neurology clinic between January 2014 and  January  2017 at were included this study. Control group included healthy controls who had compatible age and gender to the patients.  Participants’s age, gender, time of the diagnosis and the presence of RLS were recorded.  Participants with hypertension, diabetes mellitus and low ferritin level (<20 ng/mL) were excluded.

Results: Forty BD, 41 NBD patients and 39 healthy controls were included in the study. There were 67 female (55.8%) and 53 male (44.2%) in the study. Mean age was 41.6+11.2.  Female/ Male ratio was 1,5 in BD, 1 in NBD and 1,3 in the control group. Age and gender were similar in all the groups.Disease duration was 12.5+ 8.5 years in BD and 8.6+6.8 years in NBD groups. RLS frequencywas 25% in BD, 26.8% in NBD and 12.8% in control group; there was not any difference between three groups (p=0.25). Although it was not found any relationship between the presence of depression and RLS (p = 0.97), RLS was more frequent in patients with anxiety (p = 0.001). Frequency of anxiety was 73%  in patients with RLS and 35.1% in non-RLS patients (BD 50%, NBD 46.3%, control 33.3%). Frequency of depression was 61.5% in patients with RLS  and 44.6% in non-RLS patients (BD 47.5%, NBD 60.9%, control 56%).

Conclusion: RLS frequency is not different in patients with BD, NBD and healthy controls. Moreover, the presence of anxiety seems to be related with the presence of RLS.

To cite this abstract in AMA style:

M. Kuzu Kumcu, S. Erdoğan, M. Sorgun, C. Yücesan. Restless leg syndrome in Neuro-Behcet’s and Behcet’s disease [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/restless-leg-syndrome-in-neuro-behcets-and-behcets-disease/. Accessed June 15, 2025.
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