Objective: Our aim is to report an unusual case of initial manifestation of Parkinson’s disease, which showed unilateral leg tremor on sitting crossed-legged position on the floor.

Background: Unilateral leg tremor in specific position of Parkinson’s disease has very rarely reported, and unilateral leg tremor on sitting crossed-legged position on the floor associated with Parkinson’s disease have not yet been reported.

Method: Single case report.

Results: A 76-year-old woman referred to us due to unilateral leg tremor. Her neurological examination revealed not only unilateral, right-sided leg tremor on sitting crossed-legged position on the floor, but also unilateral mild parkinsonism. 18F-FP-CIT PET imaging show moderate to severe reduction of FP-CIT binding in bilateral posterior putamen, more severe in left, and so she was diagnosed as Parkinson’s disease. After medication with levodopa and dopamine agonist, symptoms of leg tremor and mild parkinsonism improved markedly.

Conclusion: For now, we report for the first time a rare initial manifestation of early-stage of Parkinson’s disease presenting unilateral leg tremor on sitting crossed-legged position on the floor. As like this case, if there are abnormal unilateral leg tremor on sitting crossed-legged position on the floor regardless of accompanying with other parkinsonism, it should be considered diagnosis of Parkinson’s disease.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/unilateral-leg-tremor-on-sitting-crossed-legged-position-as-the-initial-manifestation-of-parkinsons-disease/