Utilizing remote blood pressure monitoring in a phase III clinical drug trial for Parkinson’s disease
Objective: To determine the feasibility and value of remote blood pressure (BP) monitoring during a clinical trial of isradipine (a dihydropyridine calcium channel antagonist) in…Regional differences in the results of a phase 2b study of tozadenant in Parkinson’s disease patients with motor fluctuations
Objective: To assess how the efficacy of tozadenant differed by region in a randomized, double-blind, placebo-controlled trial of Parkinson's disease patients with motor fluctuations. Background:…The study of clinical outcome of deep brain stimulation for the idiopathic Parkinson’s disease at 6 months follow-up
Objective: The aim of this study was to assess the motor and psychiatric outcomes at 6 months after subthalamic nucleus deep brain stimulation (STN-DBS) in…Difference between physiologically defined subthalamic nucleus target and final lead placement: Influence in clinical outcome
Objective: To evaluate distance between the physiologically defined subthalamic nucleus (STN) target and final lead placement, and its influence on the clinical outcome at 6…Successful DBS: Doctors happy, patients not – Why?
Objective: Deep brain stimulation (DBS) in Parkinson's disease (PD) has been proven successful; however, not in all. Background: We report on 5 PD patients who…Comparison of four DBS lead designs under voltage and current operating modes based on patient specific simulations
Objective: To quantitatively compare the spatial extension of the electric field generated by four different lead designs operated under voltage and current modes. Background: Conventional…A prospective study of patients’ expectations in subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To prospectively assess the long-term outcome of subthalamic nucleus (STN) deep brain stimulation (DBS) and the relationship with patients' expectations and satisfaction. Background: Subthalamic…Cognitive outcome in the patients with Parkinson’s disease one year after subthalamic implants in Taiwan
Objective: To demonstrate cognitive outcome after subthalamic deep brain stimulation(DBS) in the patients with Parkinson's disease(PD) in Taiwan. Background: Deep brain stimulation of the subthalamic…DTI tractographic correlates of weight gain in Parkinson’s disease patients after STN DBS
Objective: To assess DTI connectivity patterns and correlations with weight gain in Parkinson's disease patients after STN DBS. Background: Weight gain is a well-known adverse…Prospective evaluation of pallidal deep brain stimulation in Huntington’s disease
Objective: To prospectively evaluate the effect of bilateral pallidal deep brain stimulation (DBS) on motor symptoms, activities of daily living and quality of life in…
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