Neuropsychological safety of bilateral pallidal (GPi) deep brain stimulation (DBS) for Parkinson’s disease (PD) under general anesthesia
Objective: To evaluate neuropsychological outcome of bilateral GPi DBS carried out under general anesthesia using a combination of direct anatomical targeting and intraoperative computed tomography…Clinical outcome of constant current deep brain stimulation in patients with medication-refractory essential tremor
Objective: To evaluate, for the first time, the safety and efficacy of long-term ventralis intermedius (Vim) constant current deep brain stimulation (DBS) in essential tremor…Results from a double-blind trial of pallidal DBS for Tourette’s syndrome: Are there any predictors of surgery outcome?
Objective: To explore whether individual patient characteristics can indicate response to treatment in a trial of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS)…Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy
Objective: To assess the therapeutic efficacy of the caspase-1 inhibitor prodrug VX-765 on alpha-synuclein (α-syn) pathology and neuroprotection in a transgenic mouse model of multiple…The score changes of clinical symptom assessment scales for multiple system atrophy in 2-3 years
Objective: To examine the extent of disease progression for multiple system atrophy (MSA) during relatively long duration. Background: The knowledge of MSA natural history is…The prevalence of constipation and irritable bowel syndrome in Parkinson’s disease patients according to Rome III diagnostic criteria
Objective: To assess the prevalence of constipation and irritable bowel syndrome (IBS) in Parkinson's disease (PD) patients using Rome III in our cohort. Background: Gastrointestinal…Association analysis of SNP rs11868035 in SREBF1 with Parkinson’s disease, amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population
Objective: To examine the possible genetic association of rs11868035 with Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA) in a Chinese…Frequency of echogenic abnormality of the substantia nigra is increased in methamphetamine users
Objective: To investigate structural abnormality of the substantia nigra (SN) in methamphetamine users using transcranial sonography (TCS). Background: Epidemiologic studies suggest that chronic use of…Pan American multiple system atrophy (PANMSA) consortium database
Objective: To create a database coordinating individual MSA study groups of the Pan American region with the required standards by the Global MSA Registry, as…Impact of comorbidities and compliance initiatives in management of patients with early Parkinson’s disease
Objective: To evaluate the impact of comorbidities and compliance iniciatives on treatment efficacy in patients with Parkinson's disease. Methods: In the year 2014 we included…
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