CLOCK varriant correlates to motor fluctuation and sleep disorders in Chinese patients with Parkinson’s disease
Objective: This research is to explore whether there is association between Circadian locomotor output cycle kaput (CLOCK) gene polymorphism and biological rhythm disorders of Parkinson’s…Progression to Parkinson’s disease in carriers of LRRK2 G2019S mutation: a 4-year prospective study with serial dopamine transporter imaging
Objective: To assess whether any of the biomarkers studied (UPDRS-III, SN echogenicity, UPSIT and DaT-SPECT) in a baseline evaluation of a cohort of LRRK2 G2019S asymptomatic…Characterization of Noncoding Variant(s) Driving Genome-Wide Association of the PARK10 Locus in Autopsy-Proven Parkinson Disease and Controls.
Objective: Confirm the PARK10 locus as a major GWAS locus in autopsy-confirmed (AC) PD and AC controls and identify potential noncoding variants driving the association. …Behavioral and psychological symptoms in Parkinson’s disease with SWEDDs
Objective: To assess behavioral and psychological symptoms in patients of Parkinson's disease with SWEDDs(PD-SWEDDs.. Background: Behavioral and psychological symptoms are often seen in patients with…Treatment of Psychosis in Parkinson’s Disease: Evidence-Based Recommendations Versus Actual Clinical Practice
Objective: To examine if actual clinical practice of antipsychotic use in Parkinson's Disease patients are consistent with published evidence-based reviews of treatment recommendations and discuss…How do Parkinson’s Disease patients manage Ramadan Fasting?
Objective: To describe how Parkinson's disease(PD) patients manage Ramadan fasting and the impact of the fasting period on symptoms Background: Although Ramadan fasting is not…Tongue strength in Parkinson’s disease.
Objective: To investigate tongue strength in patients with Parkinson’s disease and the relation with speech and swallowing. Background: Motor disorders in Parkinson’s disease (PD) are…Comparative Age-Relatedness of Dyskinesia, Dystonia and Ataxia Rating Scales in Healthy Children
Objective: In healthy children (4-16 years of age), we aimed to associate DIS scores with age, and compare age-related influences on dyskinesia (DIS), dystonia (BFMDRS)…VIT-D and Tics Movement Disorder
Objective: Tics is common childhood movement disorder, with classified variants , typically begin at around 4-5 years of age but often present lator at about…A Phase 2 Study of Nelotanserin, a Novel 5HT2A Receptor Inverse Agonist, in Dementia with Lewy Bodies and Parkinson’s Disease Dementia Subjects Experiencing Visual Hallucinations
Objective: To evaluate the safety and efficacy of nelotanserin in Lewy body dementia subjects experiencing visual hallucinations. Background: Nelotanserin is a selective 5HT2A receptor inverse…
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