Evaluating the Clinical Efficacy of the Personal KinetiGraph Movement Recording System
Objective: To examine the clinical efficacy of the Personal KinetiGraph (PKG) movement recording in identifying patients with Parkinson’s disease (PD) requiring treatment for motor symptoms.…Design and discovery of 1,2,4 triazole derivatives as adenosine A2A receptor antagonist against parkinson’s disease
Objective: In the present study, we intended to develop novel 1,2,4 triazole as potent A(2A)AR antagonists against parkinson’s disease. Background: Parkinson’s disease (PD) is a…Intrajejunal levodopa infusion (ILI) for Parkinson’s Disease (PD): A Canadian Experience
Objective: To review the benefits and complications of ILI for PD in a tertiary movement disorders center in Canada. Background: ILI has been in use…Botulinum Neurotoxin (BoNT) for treatment of functional (psychogenic) jerky movement disorders: a randomized placebo-controlled clinical trial
Objective: To assess the effectiveness of botulinum neurotoxin (BonT) in patients with functional jerky movement disorders Background: At least 2–9% of patients seen in movement…Treatment of secondary movement disorders related to midbrain cavernomas
Objective: To evaluate possible efficacy and safety of standard antiparkinsonian drugs (levodopa formulations, amantadine) in patients with symptomatic midbrain cavernomas (haemorhage and/or surgery) and secondary…Essential Tremor and Depression
Objective: To determine if depression and neuropsychiatric symptoms are more prevalent in patients with essential tremor (ET) compared with non-ET controls and if so, to establish…Forehead Tremor: a clinical presentation of ocular Myasthenia Gravis?
Objective: The case of a patient with seropositive Myasthenia gravis (MG), presenting with forehead tremor, is reported. Background: The clinical presentation of MG with involuntary movements…Targeting the intracellular localization of Ataxin-3 as novel treatment strategy for Spinocerebellar Ataxia Type 3
Objective: Spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) is an autosomal-dominantly inherited neurodegenerative disorder caused by a CAG expansion in the ATXN3 gene…TANDEM REPEATS BEYOND THE CLINICAL DIAGNOSIS IN ADCAs
Objective: To present observations on abnormal expansion in both allele in ADCAs. Background: Use of expansion in tandem repeats is restricted to only disease diagnosis…Eye Movements in Huntington Disease Like 2
Objective: ObjectiveTo determine if eye movements are preserved in Huntington Disease-Like 2 (HDL2) and if this can be used to differentiate HDL2 from Huntington Disease…
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