Investigation of Non-Motor Symptoms Impacting Care Dependency in Individuals with Parkinson’s Disease
Objective: To examine what extent non-motor symptoms of Parkinson’s disease (PD) predict care dependence in individuals with PD. Background: The main aim of medical management…Real-world non-motor score changes in Parkinson’s disease patients with motor fluctuations: The J-FIRST study
Objective: To identify changes in non-motor symptoms (NMSs) over time in Japanese Parkinson’s disease (PD) patients without dementia exhibiting motor fluctuations. Background: PD can cause…A global survey of the use and linguistic translation of the NMSQuest and NMSScale: implications for non-motor studies in Parkinson’s disease
Objective: To collect details of linguistic validations and translations of the non-motor symptoms questionnaire (NMSQuest) and non-motor symptoms scale (NMSScale) globally. Background: The patient completed…Translation and validation of the Filipino version of the wearing-off questionnaire-19 (F-WOQ-19)
Objective: This study aims to translate the Wearing-Off Questionnaire (WOQ) 19 into Filipino (F-WOQ-19) and validate the translated questionnaire. Background: Parkinson’s disease (PD) is a…An auditory biomarker for Parkinson’s Disease ?
Objective: In this preliminary study we aimed to investigate the nature of the differences in auditory function between patients with PD (N=25 with Hoehn and…Long-term levodopa therapy accelerates the circadian rhythm dysfunction in 6-OHDA rat model
Objective: We aimed to study the effect of L-DOPA on circadian rhythms in 6-OHDA lesioned rats, and to clarify whether the disturbance of the circadian…Self-rated burden grading of nonmotor symptoms identifies landmarks and subtypes of Parkinson’s disease: first report from a Moscow-Madrid-London collaboration
Objective: To describe clinical and imaging biomarkers of nonmotor symptoms burden (NMSB) as defined by NMS questionnaire (NMSQ) scores in a prospective international cohort study…Vmat2 heterozygote mice display motor dysfunction and progressive depressive-like behaviors
Objective: To assess motor and depressive behaviors in mice that are heterozygous for VMAT2 (VMAT2 HT). Background: Dopamine (DA) is compartmentalized by the vesicular monoamine…Association of nocturnal stridor with clinical features of patients with multiple system atrophy
Objective: To investigate the association between findings of night video-polysomnography and clinical feature of patients with multiple system atrophy (MSA). Background: Nocturnal sleep-related clinical sympotoms…Mutational analysis of COQ2 in Chinese patients with multiple-system atrophy
Objective: To investigate the involvement of COQ2 variants in Chinese sporadic cases with multiple-system atrophy. Background: Multiple-system atrophy (MSA) is a rapidly progressive neurodegenerative disease…
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