Pharmacological modulation of mGluR5 improves dyskinesias mediated by D1 but not D2 receptor stimulation.
Objective: To determine whether pharmacological inhibition of metabotropic glutamate receptor type 5 (mGluR5) can improve dyskinesias mediated by D1- or D2-type dopamine (DA) receptors (D1R…Dopamine substitution restores effective connectivity between prefrontal and premotor areas in Parkinson’s disease
Objective: To assess influences of dopamine deficiency on the causal interplay within the motor network during bimanual finger tapping in Parkinson's disease (PD) patients. Background:…Quantifying postural stability differences in people with Parkinson’s disease with and without freezing of gait, using body-worn sensors
Objective: To quantify differences in postural responses to perturbations in people with Parkinson disease (PD) with and without freezing of gait (FOG+, FOG-, resp.), using…Effects of different intensity exercises on motor function of PD rats as well as the regulation of DA
Objective: This paper research the intervention effect of the different intensity treadmill exercise on motor function of Parkinson 's diseases (PD) model rats，and explore the…Cerebrotendinous xanthomatosis without tendon xanthoma: a diagnostic challenge.
Objective: To describe the case of Cerebrotendinous xanthomatosis (CTX) without tendon xanthoma, highlighting the diagnostic challenge due to its rarity, as well as the importance…Restless Legs Syndrome in hemodialyzed patients: a case-control study.
Objective: To determine the association between the clinical and paraclinical variables and the restless legs syndrome. Background: The restless legs syndrome (RLS) is a common…Assessment of graphomotor impairment in patients with Spinocerebellar ataxia and Parkinson’s disease
Objective: The study aimed to assess the kinematic characteristics of handwriting in patients with Spinocerebellar ataxia (SCA) and to compare it with patients with Parkinson's disease…Improved Detection of Gait Abnormalities in Parkinson’s disease using an IMU Sensor-based System
Objective: To develop an automated system that uses a limited set of IMU sensors to improve the detection of gait abnormalities in Parkinson’s disease during…Alternative Apomorphine Challenge Test
Objective: To propose a new apomorphine challenge test Background: In the standard apomorphine challenge test, the appropriate dose of apomorphine is established by incremental dosing…Protocol for upper-limb kinematic analysis in paediatric movement disorders and relative normality data
Objective: The study proposes a specialised protocol to collect and analyse kinematic data from paediatric patients affected by Movement Disorders (MD). The aim is to…
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