Cortical excitability during a movement compared with postural control task in healthy subjects
Objective: To investigate cortical excitability and surround cortical inhibition during movement compared with postural control task in healthy subjects. Background: Motor control has traditionally been…Patient-reported hallucinations and the probability of progression to dementia in Parkinson’s disease
Objective: To evaluate the influence of neuropsychiatric symptoms in identifying Parkinson’s disease (PD) patients who will progress to dementia (PDD) in the imminent future (~4…The value of classical cerebrospinal fluid protein ratios and peripheral inflammation in Parkinson’s disease cognitive impairment
Objective: To evaluate cerebrospinal fluid (CSF) levels of proteins associated with neuropathological inclusions and their ratios, and CSF and plasma levels of inflammatory proteins as…Do Acetylcholinesterase Inhibitors (AChEI) delay institutionalisation in Parkinson’s and Lewy Body Disease?
Objective: We explored the use of Rivastigmine in Parkinson’s and Lewy body dementia through assessment of quantitative data obtained from a clinical database. We focussed…Effects of continuous apomorphine infusion on motor and nonmotor symptoms in Parkinson’s disease without cognitive deterioration
Objective: The aim of the present study was to investigate the influence of apomorphine pump in Parkinson’s disease (PD) on motor and nonmotor symptoms, including…Higher genetic load is associated with an earlier disease onset but not with more rapid disease progression in Parkinson’s disease
Objective: To evaluate the influence of genetic variants on phenotypic variability and disease progression in PD patients. Background: Parkinson’s disease (PD) patients show a large…A neuronal model of PARK20 (SYNJ1 mutation) using patient derived iPSCs
Objective: The SYNJ1 homozygous mutation (p.Arg258Gln) leads to juvenile Parkinsonism (PARK20). SYNJ1 plays an important role in synaptic vesicle cycling, and regulating autophagic flux. We…Glucocerebrosidase mutations in neurodegenerative disorders other than Parkinson’s disease
Objective: To determinate the frequencies of lysosomal glucocerebrosidase (GBA) common mutations in a large sample of neurodegenerative diseases including Alzheimer Disease (AD), Lewy Body Dementia (LBD), Amyotrophic…Parkinson’s disease GWAS risk loci and symptom progression
Objective: To assess whether GWAS identified Parkinson’s disease (PD) risk loci also influence symptom progression among patients. Background: Genetic factors have a considerable influence on…Predictors of onset of psychosis in Parkinson’s disease: “Who gets it early?”
Objective: To explore the factors which may predict the onset of psychosis in Parkinson’s disease (PD). Background: Non-motor symptoms (NMS) are commonly observed in PD.…
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