Movement and postural control in focal dystonia subjects measured using surface electromyography
Objective: To explore the difference in muscle activation during a postural versus movement control task in patients with focal dystonia. Background: Co-contraction of agonist and…Disease Modeling of Lesch-Nyhan Disease Using Induced Pluripotent Stem Cells
Objective: To create a resource of induced pluripotent stem cells (iPSCs) as models for exploring mechanisms of pathogenesis in Lesch-Nyhan disease (LND). Background: LND is…Prodromal features of Parkinson’s disease in women
Objective: To identify how prodromal features interact to determine Parkinson’s disease (PD) risk in women. Background: The neuronal loss that leads to PD progresses insidiously…Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation
Objective: To explore the causal relationship between circadian rhythm and Parkinson's disease (PD), and coffee consumption and PD, using Mendelian randomisation (MR). Background: Circadian rhythm…Parallel evaluation of mutant huntingtin and neurofilament light in Huntington’s disease
Objective: To assess cerebrospinal fluid (CSF) mutant Huntingtin (mHTT), and CSF and plasma neurofilament light (NfL) in Huntington’s disease (HD). Background: HD is a progressive…Exploration of insight competence in Huntington’s disease supplemental to a cognitive debriefing study for the FuRST2.0 rating scale
Objective: Evaluate insight of functional impairment in premanifest and early-manifest Huntington’s disease (HD). Background: Following the guidelines of the US Food and Drug Administration Clinical…Changes in brain network activation (BNA) in patients with fragile x-associated tremor/ataxia syndrome (FXTAS)
Objective: We aimed to assess the ability of Brain Network Activation (BNA) EEG analysis to differentiate between patients with fragile X-associated tremor/ataxia syndrome (FXTAS), Parkinson’s…Has patients affected by REM sleep Behavior Disorder a specific brain glucose metabolism pattern?
Objective: This study aimed at evaluating brain glucose metabolism in patients affected by REM sleep behavior disorders (RBD) compared to Parkinson’s Disease (PD), Lewy Body…Longitudinal alpha-synuclein in cerebrospinal fluid in early Parkinson’s disease, prodromal PD and healthy controls
Objective: To examine the longitudinal relationships between total alpha-synuclein (aSyn) changes in cerebrospinal fluid (CSF), clinical measures, and factors that may influence CSF aSyn in…Parkinson’s disease-related non-motor features as risk factors for post-operative delirium in spinal surgery
Objective: We investigated the association between PD-related NMSs and postoperative delirium in old people undergoing elective spinal surgery. Background: The clinical features of postoperative delirium…
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