High dose of levodopa and Segawa disease
Objective: To analyze the dose-dependent effects of levodopa on the symptoms of the disease in our case. Background: In 1976, Segawa et al. reported dopa-responsive…From Non-rechargeable to Rechargeable Technology: Insights and Management of Pallidal Deep Brain Stimulation in Dystonia after Switching to a Rechargeable Implantable Pulse Generator
Objective: Here, we aimed to evaluate the management of stimulation intensities after switching from NRC to RC IPG compared to previous RC-to-RC replacements. Background: Patients…The effectiveness of deep brain stimulation in dystonia: A patient-centered approach
Objective: To systematically evaluate the effectiveness of deep brain stimulation of the Globus Pallidus internus (GPi-DBS) in dystonia on pre-operatively set functional priorities in daily…Weight loss in STN DBS in Parkinson’s Disease? Long-term outcome of a prospective cohort at 5 years
Objective: To determine the long-term weight changes in Parkinson’s Disease (PD) after Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) treatment. Background: It is well-established that…Directional deep brain stimulation in Parkinson’s disease guided by local field potentials
Objective: Implementation of directional stimulation of subthalamic nucleus with segmented leads guided by local field potential (LFP) recordings in order to personalize DBS parameters, optimize…Evaluation of apathy before and after subthalamic nucleus deep brain stimulation therapy in advanced Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) has been approved to relieve the motor symptoms of Parkinson's disease (PD) patients when the optimal pharmachologic treatment is unsatisfactory.…Impact of Disease Duration and Anatomical Target on Health Related QoL in Patients Receiving DBS: Results from the Product Surveillance Registry
Objective: Summarize change in quality of life (QoL) by comparing scores from the EuroQuol-five domain questionnaire, five level response version (EQ-5D-5L) summary index obtained at…Malignant neuroleptic syndrome following a sudden deep brain stimulation battery drain: Report of two cases
Objective: In this case report we present two cases of NMS associated with sudden drain of DBS batteries (37 years old Caucasian woman and 42…Tics in Wilson’s Disease and Review of the Literature
Objective: We report a case with tics in a patient with Wilson’s Disease (WD). Background: Wilson’s disease is a genetic disorder of copper metabolism, leading…Loss of paraplegin drives spasticity rather than ataxia in SPG7: A European cohort analysis of 238 patients
Objective: The aim of this work was to delineate the clinical phenotype of SPG7 patients, integrating genetic data and follow-up examinations, taking advantage of a…
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