Primary familial brain calcification – The impact of calcifications on the development of motor symptoms
Objective: The aim of the present study was to investigate whether the nigro-striatal system in a genetic mouse model of primary familial brain calcification (PFBC)…High amplitude jerky tremor in developmental dopamine deficiency
Objective: To describe the phenomenology of tremor in infantile parkinsonism due to dopamine deficiency. Background: Parkinsonism in childhood is usually caused by genetic abnormality, including…Diagnostic tips from a case series of patients with Late Onset Tay Sachs disease
Objective: To describe a population of eight patients with Late Onset Tay Sachs (LOTS) disease and offer tips to aid in diagnosing this rare condition.…Chitotriosidase is a biomarker for Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)
Objective: ALSP belongs to the large group of rare neurogenetic, adult-onset leukodystrophies. For most of these leukodystrophies, including ALSP, no causative treatment exists. Biomarkers facilitate…Deep brain stimulation: A Treatment Modality for Generalized Dystonia Secondary to Anoxic Brain Injury in Adults
Objective: To report a case of severe generalized dystonia secondary to anoxic brain injury treated successfully with bilateral globus pallidus interna (GPi) deep brain stimulation…Predictor for speech deterioration following STN-DBS in PD patients
Objective: We conducted a 2-year prospective study of PD patients treated with subthalamic nucleus deep brain stimulation (STN-DBS) to elucidate the predictive factors of deterioration…Subthalamic neuromodulation restores motor learning in Parkinson’s disease
Objective: The aims of the present study were to (i) investigate the effect of subthalamic deep brain stimulation (STN-DBS) on motor learning in Parkinson’s disease…Attitudes toward earlier use of deep brain stimulation among patients with Parkinson’s disease
Objective: To explore Parkinson’s patient experiences with Deep Brain Stimulation (DBS) and attitudes towards earlier use of DBS. Background: In November 2015 the U.S. Food…The effects of deep brain stimulation of the pedunculopontine nucleus on cognition in Parkinson’s disease and Progressive Supranuclear Palsy
Objective: To investigate the effects of deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) on different cognitive domains for Parkinson’s disease (PD) and progressive…Impact of STN-DBS on Medication Reduction
Objective: We aim to evaluate the efficacy of subthalamic nucleus deep brain stimulation on reducing medication in Parkinson´s disease patients. Background: Parkinson's disease (PD) is…
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