Burden of Eye disease in Parkinson’s disease (PD)
Objective: To review the burden of eye pathologies in patients with Parkinson’s disease. Background: Parkinson’s disease and eye problems are common in older patients. Alterations…Study of prevalence of non-motor symptoms in typical and atypical parkinsonism as compared to age and sex matched healthy controls
Objective: 1) To study prevalence and clinical characteristics of non-motor symptoms (NMS) in idiopathic parkinson disease (IPD) and atypical Parkinsonism (APD) as compared to age…Is REM sleep behavior disorder associated with excessive daytime sleepiness in military veterans with Parkinson’s disease?
Objective: To determine if REM sleep behavior disorder (RBD) is associated with excessive daytime sleepiness (ES) in military veterans with Parkinson’s disease (PD). Background: Nearly…Multimorbidity predicts quality of life but not motor severity in early Parkinson’s disease
Objective: To explore the associations between multimorbidity, severity of motor symptoms, and quality of life (QoL) in people with early PD. Background: Multimorbidity is defined…Gastrointestinal Symptoms and Enteric Nerve Dysfunction in A53T Mice
Objective: To investigate the relationship between α synucleinopathy-induced enteric neuropathy and gastrointestinal dysfunction in A53T mice. Background: Approximately 80-90% of PD patients suffer from GI…Degeneration of vagus nerve but not of accessory and phrenic nerve in Parkinson’s disease revealed by high-resolution ultrasound
Objective: To test the hypothesis that the vagus nerve is measurably atrophic in idiopathic Parkinson’s disease (PD). Background: The vagus nerve is discussed to represent…Restless legs syndrome in Parkinson’s disease patients: a comparative study on prevalence, clinical features, motor and non-motor symptoms
Objective: We investigate the prevalence of restless legs syndrome in Parkinson’s disease patients and to identify associated clinical features, motor and non-motor symptoms. Background: Restless…Comorbid REM sleep behavior disorder and impulse control disorder symptoms in early parkinson’s disease: The PPMI cohort
Objective: To assess the prevalence of Impulse Control Disorder symptoms (ICD) in Parkinson's disease with probable REM sleep behavior disorder (i.e. RBD assessed by questionnaire,…Risk estimation in the years preceding diagnosis of Parkinson’s disease in the PREDICT-PD cohort
Objective: To test and refine the use of probability-based algorithms to identify individuals at high-risk of developing Parkinson’s disease (PD). Background: Neurodegeneration preceding a formal…Pharmacological modulation of lysosomal glucocerebrosidase activity in the Thy1-aSYN mouse model of Parkinson’s disease
Objective: To study the pharmacological modulation of glucocerebrosidase activity in the Thy1-aSYN mouse model of Parkinson's disease (PD). Background: PD is a complex neurodegenerative disorder…
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