Fragile X-associated tremor/ataxia syndrome, Parkinson’s disease, and essential tremor subjects demonstrate distinct tremor characteristics using quantitative tremorography
Objective: To compare Fragile X-associated tremor/ataxia syndrome (FXTAS), Parkinson disease (PD), essential tremor (ET) and controls using quantitative measures of tremor. Background: FXTAS, a progressive…Alternating thalamic deep brain stimulation for Essential Tremor: A trial to reduce habituation
Objective: We propose a novel approach to the treatment paradigm for deep brain stimulation (DBS) programming in the ventral intermediate nucleus (VIM) for patients with…Effect of striatal dopamine depletion on cognition in de novo Parkinson’s disease
Objective: To investigate the relationship between the sub-regional pattern of striatal dopamine depletion and cognitive impairment in early-stage Parkinson’s disease (PD), and determine the effect…Curcumin improves cognitive function in rotenone-induced rat model of Parkinson’s disease (PD)
Objective: In this study, we aimed to investigate the neuroprotective effect of curcumin against rotenone-induced memory impairments in rat PD model. Background: In PD, oxidative…Using Vision to Predict Dementia in Parkinson’s Disease
Objective: To identify visual measures that relate to higher risk of dementia in Parkinson’s Disease (PD). Background: Dementia affects 50% of people with PD within…The development of an instrument for measuring Parkinson’s patient empowerment
Objective: To develop a valid and reliable measurement scale of Parkinson’s patient empowerment index (PPEI). Background: Patient empowerment concept has been used as part of…Change of Cognition Functions after Subthalamic Nucleus-Deep Brain Stimulationin in Parkinson’s Disease
Objective: To explore the changes of cognitive function in Parkinson disease (PD) patients with deep brain stimulation (DBS) of the subthalamic nucleus (STN). Background: STN-DBS…Adult neurogenesis is impaired in pink1-/- zebrafish (Danio rerio)
Objective: To determine whether PINK1 deficiency impairs adult neurogenesis in a tractable vertebrate model of PINK1-related Parkinson's disease (PD). Background: PD is characterized by loss…Mitochondrial phenotype related to the A30P alpha-synuclein mutation as a patient-derived cellular model of Parkinson’s disease
Objective: Our study aims to perform detailed phenotyping of the A30P alpha-synuclein familial case of PD, allowing to identify underlying mechanisms of the disease that…A review of modifiers of Parkinsonism in the Leucine-rich repeat kinase 2 (LRRK2) population
Objective: To review and examine the most current identified modifiers of Parkinsonism in the LRRK2 population. Background: LRRK2 is a protein with multiple domains and…
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