MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Ginsenoside Rb1 protects dopaminergic neurons through Foxm1-Nurr1 pathway in mice model of Parkinson’s disease

    T. Zhou, X. Huang, L. Li, J. Yang, Z. Liang (Dalian, China)

    Objective: In the present work, we investigated the protective effects of ginsenoside Rb1 in dopaminergic neurons through Foxm1-Nurr1 pathway in mice model of Parkinson’s disease.…
  • 2018 International Congress

    Cortical myoclonus explained by cerebellar dysfunction: Evidence from a unique case

    L. Rocchi, L. Latorre, J. Rothwell, K. Bhatia (London, United Kingdom)

    Objective: To give a thorough neurophysiological description of a patient presenting with unilateral cortical myoclonus and homolateral congenital cerebellar hemiatrophy Background: The role of the…
  • 2018 International Congress

    Effect of finger rhythmic movement training on freezing of gait in Parkinson’s disease patients: A study protocol

    H. Nakano, S. Murata, T. Kodama, H. Nakae, M. Soma (Kyoto-city, Japan)

    Objective: To investigate the effect of finger rhythmic movement (FRM) training on freezing of gait (FOG) in Parkinson's disease (PD) patients. Background: External cues such…
  • 2018 International Congress

    Effects of the Lee Silverman Voice Treatment (LSVT LOUD ®) on Facial Expressivity in Individuals with Parkinson’s Disease (PD) as a function of Emotional Valence

    A. Bono, K. Scorpio, R. Stafford, M. Halfacre, E. Murray, J. Twaite, K. Alterescu, J. Spielman, A. Halpern, L. Ramig, J. Borod (Flushing, NY, USA)

    Objective: To examine the effect of LSVT LOUD (Ramig et al., 2011) on facial expressivity in PD as a function of emotional valence. Background: Research…
  • 2018 International Congress

    The anti-dyskinetic effect of the clinically-available 5-HT3 receptor antagonist granisetron in the 6-OHDA-lesioned rat model of Parkinson’s disease

    C. Kwan, I. Frouni, D. Bedard, A. Hamadjida, P. Huot (Montreal, QC, Canada)

    Objective: To determine the effect of the serotonin 3 (5-HT3) receptor antagonist granisetron, a clinically-available anti-emetic, on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia. Background: Dopamine replacement with L-DOPA…
  • 2018 International Congress

    Relationship between Patient Global Impression of Change and other Efficacy Endpoints in Parkinson’s Disease: A post-hoc analysis from combined BIPARK-I and II

    J. Ferreira, W. Poewe, O. Rascol, R. Costa, E. Arbe, J-F. Rocha, P. Soares-da-Silva (Lisbon, Portugal)

    Objective: To evaluate the association of patients’ perception of Parkinson’s Disease (PD) symptoms improvement (as assessed by Patient Global Impression of Change, PGIC) could be…
  • 2018 International Congress

    The combined effect of repetitive transcranial magnetic stimulation and treadmill training in people with Parkinson’s disease – A randomized controlled trial

    C. Chung, M. Mak, M. AuYeung, Y. Chan, N. Cheung, V. Mok, M. Hallett (Hong Kong, Hong Kong)

    Objective: To evaluate the combined effect of repetitive transcranial magnetic stimulation (rTMS) on treadmill training in people with Parkinson’s disease (PD). Background: Previous studies showed…
  • 2018 International Congress

    DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Visualization of Optimal Directionally Stimulated Anatomy

    F. Steigerwald, J. Volkmann, C. Matthies, A. Dalal Kirsch, S. Chabardes, R. de Bie, PR. Schuurman, E. Moro, V. Fraix, S. Meoni, D. Blum, L. Juarez Paz, K. Wynants, N. Van Dyck (Würzburg, Germany)

    Objective: To visualize the volumes of activated tissue in relation to the neuroanatomy for the optimal stimulation parameters in Ring Mode (omnidirectional) stimulation in comparison…
  • 2018 International Congress

    Quantitative assessment of the effectiveness of adaptive Deep Brain Stimulation in Parkinson’s disease

    D. Piña-Fuentes, M. Tijssen, M. Oterdoom, S. Little, J. van Zijl, T. van Laar, P. Brown, M. van Dijk, M. Beudel (Groningen, Netherlands)

    Objective: To determine the effectiveness of Adaptive Deep Brain Stimulation (aDBS) in PD patients compared to cDBS and non-medicated PD patients (OFF). Background: aDBS based…
  • 2018 International Congress

    The Effect of Conduction Exercise and Self-acupressure in Treatment of Parkinson’s Disease: A Pilot Study

    M. Li, K.K. Chua, C.S. Yuen, Z.Y. Zhuang, W.H. Lau, H.Y. Chow (Hong Kong)

    Objective: To evaluate the efficacy and safety of exercise regime combining Conduction exercise (CE) and self-acupressure (SA) in treating both motor symptoms (MS) and non-motor…
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