MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    The Polymorphism of SREBF1 Gene rs11868035 G/A Is Associated with susceptibility to Parkinson’s disease in a Chinese Population

    F. Lou, M. Li, XG. Luo, Y. Ren (Shenyang, China)

    Objective: The potential association between the single-nucleotide polymorphism of two functional genes (SREBF1gene rs11868035 and USP25 gene rs2823357) and susceptibility to Parkinson’s disease (PD) in…
  • 2018 International Congress

    Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors

    T. Falzone, L. Cromberg, M. Alloatti, I. Fernandez Bessone, T. Saez (Buenos Aires, Argentina)

    Objective: In this study we aim to elucidate the role of Kif5b motor subunit in the nigrostriatal pathway. We have generated different conditional knockout mice…
  • 2018 International Congress

    Genetic variations of SNCA and striatal dopaminergic dysfunction in patients with Parkinson’s disease

    MJ. Lee, K. Pak (Busan, Korea)

    Objective: The aim of the present study was to investigate genetic variants in SNCA associated with accelerated deterioration in striatal dopaminergic activity. Background: Widespread a-synuclein…
  • 2018 International Congress

    A pilot study of plasma ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) as a potential blood-based biomarker in Parkinson’s disease

    A. Ng, YJ. Tan, ZH. Lu, S. Ng, E. Ng, F. Setiawan, N. Keong, WL. Au, EK. Tan, L. Tan (Singapore, Singapore)

    Objective: To determine plasma levels of UCH-L1 in patients with PD, and to investigate the association with both genetic (leucine-rich repeat kinase 2, LRRK2 and…
  • 2018 International Congress

    Longitudinal changes in Neuromelanin MRI Signal in Parkinson’s Disease

    R. Gaurav, N. Pyatigorskaya, C. Ewenczyk, R. Valabregue, K. Evans, I. Arnulf, M. Vidailhet, S. Lehéricy (Paris, France)

    Objective: To examine the longitudinal changes in neuromelanin (NM) MRI signal in the substantia nigra (SN) in Parkinson’s disease (PD). Background: PD is characterized by…
  • 2018 International Congress

    Transcranial imaging of substantia nigra hyperechogenicity in a Chinese cohort of Parkinson’s disease

    G. Hongling, Y. Qingmei (Wuhan, China)

    Objective: In this research we set out to study the diagnostic value of TCS in Parkinson's disease. Background: An increased echogenicity of the substantia nigra…
  • 2018 International Congress

    Improvement of antisaccade amplitude by the STN DBS and target eccentricity

    A. Yugeta, Y. Terao, Y. Ugawa (Tokyo, Japan)

    Objective: To investigate the dependency of antisaccade (AS) amplitude improvement by the subthalamic nucleus (STN) deep brain stimulation (DBS) on the target eccentricity in Parkinson’s…
  • 2018 International Congress

    The usefulness of 18 F-DOPA PET scan in diagnostically challenging patients at a movement disorder clinic

    M. Khider, A. Dorutyer, J. Warwick, J. Carr (Cape Town, South Africa)

    Objective: The aim of this study was to determine the usefulness of 18 F-DOPA PET scan in diagnostically challenging patients at our movement disorder clinic…
  • 2018 International Congress

    Changes in cortical thickness in patients with early Parkinson’s disease at different Hoehn and Yahr stages

    Y. Gao, K. Nie, M. Mei, M. Guo, Z. Huang, L. Wang, J. Zhao, B. Huang, Y. Zhang, L. Wang (Guangzhou, China)

    Objective: This study was designed to explore changes in cortical thickness in patients with early Parkinson's disease (PD) at different Hoehn and Yahr (H-Y) stages…
  • 2018 International Congress

    The effect of age on Substantia Nigra Hyperechogenicity in PD patients and healthy controls

    T. Toomsoo, A-H. Pool, I. Liepelt–Scarfone, L. Kadastik-Eerme, I. Rubanovits, T. Asser, D. Berg, P. Taba (Tallinn, Estonia)

    Objective: To analyze whether the size of SN+ is differentially affected depending on disease start side. Secondly to analyze the interaction between a range of…
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