Lottery choice task as a detect tool for PD patients with pathological gambling
Objective: We aim to develop a tool lack of stigma to detect patients' impulse control problems. Background: Dopaminergic medication is current major treatment for Parkinson's…Single-centre open label exploratory phase IIb pilot study of exogenous oral Melatonin for the treatment of Nocturia in adults with Parkinson’s disease
Objective: To evaluate the effect of melatonin on nocturia. Background: Nocturia is one of the commonest non motor symptoms in Parkinsons’ disease (PD), and has…Efficacy of liquid sinemet on non-motor symptoms in Parkinson’s disease
Objective: To investigate the short term effect of liquid sinemet on the non-motor symptoms of people with advanced Parkinson’ disease (PD) who experience complex motor…Effects of neural stem cell transplantation on the differentiation of dopaminergic neurons in the substantia nigra and changes to rotational behavior of Parkinson’s disease rats
Objective: To explore the effects of neural stem cells transplantation on the differentiation of substantia nigra dopaminergic neurons and on the rotational behavior in a…B lymphocytes may be protective in early Parkinson’s disease and in an animal model of dopaminergic cell death
Objective: To investigate B lymphocyte phenotype and function in human PD and in an animal model of disease. Background: The clinical course in Parkinson’s disease…Insulin degrading enzyme, a novel key protein against alpha-synuclein oligomers formation?
Objective: The objective of this work is to study the interaction between α-synuclein and the insulin degrading enzyme in the pancreas of subjects with synucleinopathies.…Freezing of Gait in Parkinson’s Disease: Clinico-biochemical Observations
Objective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…Vascular risk factors prevalence differences between Vascular Parkinsonism (VaP) and Parkinson Disease (PD) in a hospital cross-section study
Objective: Determine and compare vascular risk factors between VaP and PD patients in a hospital-based sample. Background: Most studies demonstrate that vascular risk factors are…Investigating the role of microRNA biogenesis pathway in neuroprotection in primary neuronal culture model of Parkinson’s disease
Objective: Here we study the effect of microRNAs (miRs) biogenesis on the dopamine (DA) neuronal maintenance and protection from different stressor-induced insults. Background: Despite many…Depression (BDI-II) in Parkinson’s disease: Prevalence, types, and variables associated to major, minor and subclinical depression in COPPADIS cohort
Objective: To know the prevalence and characteristics of depression in PD patients of the COPPADIS-2015 cohort and its relationship with the other clinical aspects of…
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